Results 71 to 80 of about 27,388,041 (218)

Molecular Modeling in Drug Design [PDF]

open access: yesMolecules, 2019
This Special Issue contains thirteen articles that provide a vivid snapshot of the state-of-the-art of molecular modeling in drug design, illustrating recent advances and critically discussing important challenges [...]
Outi M. H. Salo-Ahen   +2 more
openaire   +5 more sources

Early transcriptional and cellular abnormalities in choroid plexus of a mouse model of Alzheimer’s disease

open access: yesMolecular Neurodegeneration
Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the accumulation of amyloid-β plaques, tau hyperphosphorylation, and neuroinflammation.
Zhong-Jiang Yan   +4 more
doaj   +1 more source

Towards a Cure for Diamond–Blackfan Anemia: Views on Gene Therapy

open access: yesCells
Diamond–Blackfan anemia (DBA) is a rare genetic disorder affecting the bone marrow’s ability to produce red blood cells, leading to severe anemia and various physical abnormalities.
Matilde Vale   +2 more
doaj   +1 more source

Molecular mimicry between tumor associated antigens and microbiota-derived epitopes

open access: yesJournal of Translational Medicine, 2022
Background The gut microbiota profile is unique for each individual and are composed by different bacteria species according to individual birth-to-infant transitions.
Concetta Ragone   +7 more
doaj   +1 more source

Transport of Molecular Motor Dimers in Burnt-Bridge Models

open access: yes, 2007
Dynamics of molecular motor dimers, consisting of rigidly bound particles that move along two parallel lattices and interact with underlying molecular tracks, is investigated theoretically by analyzing discrete-state stochastic continuous-time burnt ...
Alexander Yu Morozov   +5 more
core   +1 more source

Stargardt disease: clinical features, molecular genetics, animal models and therapeutic options

open access: yesBritish Journal of Ophthalmology, 2016
Stargardt disease (STGD1; MIM 248200) is the most prevalent inherited macular dystrophy and is associated with disease-causing sequence variants in the gene ABCA4.
Preena Tanna   +3 more
semanticscholar   +1 more source

Effects of starter cultures on the metabolite profile, antioxidant activities, and anti-aging properties of tapuy lees

open access: yesDiscover Food
The Philippine rice wine (tapuy) and tapuy lees making process utilizes bubod, the traditional starter culture. The bubod contains variable number and species of microorganisms and influences the physical and chemical properties of tapuy and tapuy lees ...
Edward Kevin B. Bragais   +1 more
doaj   +1 more source

Dynamic Properties of Molecular Motors in Burnt-Bridge Models

open access: yes, 2007
Dynamic properties of molecular motors that fuel their motion by actively interacting with underlying molecular tracks are studied theoretically via discrete-state stochastic ``burnt-bridge'' models.
Alexander Yu Morozov   +8 more
core   +1 more source

Molecular Model of the Contractile Ring [PDF]

open access: yesPhysical Review Letters, 2005
PACS numbers: 87.16.Ka, 87.16.Ac http://www.ncbi.nlm.nih.gov/pubmed/16197254 http://www.weizmann.ac.il/complex/tlusty/papers/PhysRevLett2005 ...
Biron, D   +3 more
openaire   +5 more sources

Cytoscape: a software environment for integrated models of biomolecular interaction networks.

open access: yesGenome Research, 2003
Cytoscape is an open source software project for integrating biomolecular interaction networks with high-throughput expression data and other molecular states into a unified conceptual framework.
Paul Shannon   +8 more
semanticscholar   +1 more source

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