Results 71 to 80 of about 26,891,998 (226)

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors

Nature Communications, 2017
Colorectal carcinoma represents a heterogeneous entity, with only a fraction of the tumours responding to available therapies, requiring a better molecular understanding of the disease in precision oncology.
M. Schütte, T. Risch, Nilofar Abdavi-Azar, K. Boehnke, Dirk Schumacher, Marlen Keil, Reha Yildiriman, Christine Jandrasits, T. Borodina, V. Amstislavskiy, Catherine L. Worth, C. Schweiger, S. Liebs, M. Lange, H. Warnatz, L. Butcher, J. Barrett, M. Sultan, C. Wierling, N. Golob-Schwarzl, S. Lax, S. Uranitsch, M. Becker, Y. Welte, Joseph L. Regan, M. Silvestrov, I. Kehler, A. Fusi, T. Kessler, R. Herwig, U. Landegren, Dirk Wienke, M. Nilsson, J. Velasco, P. Garin‐Chesa, C. Reinhard, S. Beck, R. Schäfer, C. Regenbrecht, D. Henderson, B. Lange, J. Haybaeck, U. Keilholz, J. Hoffmann, H. Lehrach, M. Yaspo   +45 more
semanticscholar   +1 more source

Molecular Dynamics Study of Polarizable Ion Models for Molten AgBr [PDF]

, 2006
Three different polarizable ion models for molten AgBr have been studied by molecular dynamics simulations. The three models are based on a rigid ion model (RIM) with a pair potential of the type proposed by Vashishta and Rahman for alpha-AgI, to which ...
Bitrian, V., Trullas, J.
core   +1 more source

Tumor Cellular and Microenvironmental Cues Controlling Invadopodia Formation

Frontiers in Cell and Developmental Biology, 2020
During the metastatic progression, invading cells might achieve degradation and subsequent invasion into the extracellular matrix (ECM) and the underlying vasculature using invadopodia, F-actin-based and force-supporting protrusive membrane structures ...
Ilenia Masi, Valentina Caprara, Anna Bagnato, Laura Rosanò, Laura Rosanò   +4 more
doaj   +1 more source

Molecular Models of Hydroxide, Oxyhydroxide, and Clay Phases and the Development of a General Force Field

, 2004
The fate of chemical and radioactive wastes in the environment is related to the ability of natural phases to attenuate and immobilize contaminants through chemical sorption and precipitation processes. Our understanding of these complex processes at the
R. Cygan, †‡ and Jian-Jie Liang, A. Kalinichev   +2 more
semanticscholar   +1 more source

MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods.

Molecular biology and evolution, 2011
Comparative analysis of molecular sequence data is essential for reconstructing the evolutionary histories of species and inferring the nature and extent of selective forces shaping the evolution of genes and species.
K. Tamura, D. Peterson, N. Peterson, G. Stecher, M. Nei, Sudhir Kumar   +5 more
semanticscholar   +1 more source

Animal Models of Parkinson’s Disease

The Hidden Life of the Basal Ganglia, 2021
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta, the consequent dopamine deficit in the striatum and the accumulation of aggregated α‐ synuclein (α ...
I. T. Damas, Ana Quiroga ‐ Varela, N. L. Rey   +2 more
semanticscholar   +1 more source

Molecular mimicry between tumor associated antigens and microbiota-derived epitopes

Journal of Translational Medicine, 2022
Background The gut microbiota profile is unique for each individual and are composed by different bacteria species according to individual birth-to-infant transitions.
Concetta Ragone, Carmen Manolio, Angela Mauriello, Beatrice Cavalluzzo, Franco M. Buonaguro, Maria Lina Tornesello, Maria Tagliamonte, Luigi Buonaguro   +7 more
doaj   +1 more source

In vitro screening and characterization of lactic acid bacteria from Lithuanian fermented food with potential probiotic properties

Frontiers in Microbiology, 2023
The present work aimed to identify probiotic candidates from Lithuanian homemade fermented food samples. A total of 23 lactic acid bacteria were isolated from different fermented food samples.
Ashwinipriyadarshini Megur, Eric Banan-Mwine Daliri, Toma Balnionytė, Jonita Stankevičiūtė, Eglė Lastauskienė, Aurelijus Burokas   +5 more
doaj   +1 more source

Extended master equation models for molecular communication networks

, 2013
We consider molecular communication networks consisting of transmitters and receivers distributed in a fluidic medium. In such networks, a transmitter sends one or more signalling molecules, which are diffused over the medium, to the receiver to realise ...
Chou, Chun Tung
core   +1 more source

Stargardt disease: clinical features, molecular genetics, animal models and therapeutic options

British Journal of Ophthalmology, 2016
Stargardt disease (STGD1; MIM 248200) is the most prevalent inherited macular dystrophy and is associated with disease-causing sequence variants in the gene ABCA4.
Preena Tanna, R. Strauss, K. Fujinami, M. Michaelides   +3 more
semanticscholar   +1 more source