Results 91 to 100 of about 25,343,255 (333)

Organizational Behavior in the Knowledge Based Society, a Practical Research in the Romanian Business Environment [PDF]

open access: yes
The paper contains the results of a special research developed by the author on the organizational behavior in some multinational companies with branches in Romania.
Armenia ANDRONICEANU
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The Ways of Improving the Activity of Free Economic Zones in the Republic of Moldova [PDF]

open access: yesRisk in Contemporary Economy, 2011
General approach about such economical-organizational structures as free economic zones, is very large and changeable because of faster evolution of the factors that influence their development, and which further generate a great number of specifically ...
Angela OSMATESCU
doaj  

Perfis de profissionalização: um contributo sociológico para a compreensão das ONGD portuguesas

open access: yesSociologia: Revista da Faculdade de Letras da Universidade do Porto, 2017
In the scope of the debate on the (in)effectiveness of development aid, this article seeks to discuss the organizational and management models of Non-Governmental Development Organizations (NGDOs) in terms of their higher and lower orientation towards ...
Vanessa Marcos
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Modelos de gestão flexíveis a partir de mudanças na cultura organizacional alicerçada no empreendedorismo

open access: yesRevista de Ciências da Administração : RCA, 2003
The search for survival before world-wide market, allied to the influence of new technologies, has obliged managers to promote changes in the organizational culture.
Fabiano Maury Raupp, Ilse Maria Beuren
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Generic Process Transformation Model: Transition to Process-based Organization [PDF]

open access: yes
The competitive global market climate of the new millennium has raised awareness of business processes as the most important management paradigm (Levi, 2002).
Tomislav Hernaus
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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