Results 101 to 110 of about 192,740 (318)
Revista de Ciências da Administração : RCA, 2003 The search for survival before world-wide market, allied to the influence of new technologies, has obliged managers to promote changes in the organizational culture.
Fabiano Maury Raupp, Ilse Maria Beuren
doaj
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Reference Modeling for Inter-organizational Systems
, 2010 Inter-organizational business process models are created and used by different partner networks. Often, those models are similar but differ in certain business needs.
Mayrhofer, Dieter
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Impact of Servitized Corporate Models in Providing A Competitive Edge to The Manufacturing Industry
JTRMThis document reviews the impact of servitization on manufacturing companies' corporate models. It discusses how product-centric firms can transition to service-oriented models by incorporating software services into their offerings.
S M Nazmuz Sakib
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
This paper examines the dynamic and multi-level relationship between organization and innovation from three different but interdependent perspectives: a) the relationship between organizational structural forms and innovativeness; b) innovation as a ...
Lam, Alice
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Organizational Models for Non-Core Processes Management: A Classification Framework
International Journal of Engineering Business Management, 2012 This study investigates the impact of different organizational models for the management of non-core processes in the facility management (FM) industry and seeks to suggest which is the best in terms of strategic and operative advantages and ...
Alberto F. De Toni +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Standard Operating Procedures and Organizational Learning [PDF]
We report results of a study on processes of Organizational Learning (OL). Changes and suspensions of organizational rules are taken as indicators for OL. The empiric analysis is performed with personnel rules of a German bank. The aim of our study is to
Beck, Nikolaus, Kieser, Alfred
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