Results 111 to 120 of about 3,006,601 (299)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Mathematics and fisheries: Match or mismatch?

Electronic Journal of Differential Equations, 2005
Mathematics plays a major role in contemporary fisheries management. Stock assessments often depend on elaborate models used to set catch levels and address other policy objectives.
Jon T. Schnute
doaj  

Statistical Models and Invariance

The Annals of Mathematical Statistics, 1967
Brillinger [2] gives necessary and sufficient conditions for a model to be invariant under a Lie group of transformations. The problems that can be handled by his conditions are surveyed, and found effectively to be restricted to one-dimensional problems amendable to Lindley's [8] method and to problems connected with conflicts between Bayes' and ...
openaire   +2 more sources

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

U-Turn Diffusion

Entropy
We investigate diffusion models generating synthetic samples from the probability distribution represented by the ground truth (GT) samples. We focus on how GT sample information is encoded in the score function (SF), computed (not simulated) from the ...
Hamidreza Behjoo, Michael Chertkov
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Statistical Challenges in Development of Prognostic Models in Diffuse Large B-Cell Lymphoma: Comparison Between Existing Models – A Systematic Review

Clinical Epidemiology, 2020
Jelena Jelicic,1 Thomas Stauffer Larsen,1,2 Henrik Frederiksen,1,2 Bosko Andjelic,3 Milos Maksimovic,4 Zoran Bukumiric5 1Department of Hematology, Odense University Hospital, Odense, Denmark; 2Department of Clinical Research, University of Southern ...
Jelicic J, Larsen TS, Frederiksen H, Andjelic B, Maksimovic M, Bukumiric Z   +5 more
doaj  

Statistical Policy Working Paper 27. Training for the Future: Addressing Tomorrow\u2019s Survey Tasks

The subcommittee reviewed training and development at its six member agencies \u2014 Bureau of the Census, Bureau of Labor Statistics, Centers for Disease Control and Prevention, Energy Information Administration, National Agricultural Statistics Service,
United States. Federal Committee on Statistical Methodology. Subcommittee on Survey and Statistical Training
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source