Results 41 to 50 of about 1,353,306 (266)

CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting

Nature Communications
Chimeric antigen receptor (CAR)-T cell therapy has transformed the treatment of B-cell malignancies, but its success in acute myeloid leukemia (AML) remains limited.
Ari Itoh-Nakadai, Minggao Liang, Michiho Shindo, Chen Bibi, Mariko Tomizawa-Murasawa, Saera Fujiki, Akiko Kaneko, Emi Kanamaru, Mari Hashimoto, Hiroshi Kajita, Yoshinari Ando, Miki Kojima, Jonathan Moody, Makoto Iwasaki, Shinsuke Takagi, Ryo Nakagawa, Saumya Agrawal, Hanae Amitani-Iijima, Kaori Sato, Yuriko Sorimachi, Nahoko Suzuki, Takehiro Fukami, Kazuharu Hanada, Satoshi Morita, Kazushige Katsura, Takehisa Matsumoto, Maiko Kobayashi, Masahiko Kato, Yasuyuki Negishi, Mikako Shirouzu, Yuho Najima, Keiyo Takubo, Chung Chau Hon, Naoyuki Uchida, Shuichi Taniguchi, Yukihide Momozawa, Piero Carninci, Leonard D. Shultz, Yoriko Saito, Michiel de Hoon, Jay W. Shin, Fumihiko Ishikawa   +41 more
doaj   +1 more source

Modelling the term structure

Financial Markets and Portfolio Management
Abstract Based on an analysis of changes in the yields of German government bonds, we propose a simple model for the term structure of interest rates and show that this model with two parameters (relating to the interest level and slope of the term structure) fits empirically well the data for a change horizon of one year or longer ...
Christoph Memmel, Lotta Heckmann-Draisbach   +1 more
openaire   +3 more sources

Structured Modeling with GRACE

Electronic Notes in Theoretical Computer Science, 2002
Abstract In this paper, we sketch and illustrate the structuring concepts of the graph- and rule-centered modeling language GRACE , including transformation units, formal parameter units, transformation modules, and their composition to modular systems.
Hans-Jörg Kreowski, Giorgio Busatto, Renate Klempien-Hinrichs, Peter Knirsch 0001, Sabine Kuske   +4 more
openaire   +1 more source

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla, Sean Carter, Andrew Wood, Sandra Staffieri, Andrew Dodgshun, David D. Eisenstat, Michael Sullivan   +6 more
wiley   +1 more source

Fluid Net Models: From Behavioral Properties to Structural Objects

Applied Sciences, 2022
Increasing the production in manufacturing systems is one of the main demands in modern systems. The naive approach that this goal can be achieved when more or faster resources are used is not always valid.
Manuel Navarro-Gutiérrez, Antonio Ramírez-Treviño, Manuel Silva   +2 more
doaj   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

A preliminary study of the nonlinearity of adhesive point-fixings in structural glass facades

Journal of Facade Design and Engineering, 2015
The recent demand for architectural transparency has drastically increased the use of glass material for structural purpose. However, connections between structural glass members represent one of the most critical aspects of glass engineering, due to the
Jonas Dispersyn, Manuel Santarsiero, Jan Belis, Christian Louter   +3 more
doaj  

Structural models of emotional freedom

ACROSS
The study synthesizes theoretical perspectives on the structural models of emotional freedom and emphasizes that the development of this skill significantly impacts people's quality of life.
Claudia Elena STOICA
doaj   +1 more source

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

BayesX: Analyzing Bayesian Structural Additive Regression Models

Journal of Statistical Software, 2005
There has been much recent interest in Bayesian inference for generalized additive and related models. The increasing popularity of Bayesian methods for these and other model classes is mainly caused by the introduction of Markov chain Monte Carlo (MCMC)
Thomas Kneib, Andreas Brezger, Stefan Lang   +2 more
doaj   +3 more sources