Results 61 to 70 of about 4,027,766 (293)

A preliminary study of the nonlinearity of adhesive point-fixings in structural glass facades

Journal of Facade Design and Engineering, 2015
The recent demand for architectural transparency has drastically increased the use of glass material for structural purpose. However, connections between structural glass members represent one of the most critical aspects of glass engineering, due to the
Jonas Dispersyn, Manuel Santarsiero, Jan Belis, Christian Louter   +3 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Structural Assessment of Flexible Pavements Based on the Level of Detail of Management Functions

Ingeniería
Context: Pavement condition data are a fundamental component of pavement management systems (PMS) and play a critical role in structural evaluation.
Edwin Antonio Guzmán Suárez, Diego Fernando Gualdrón Alfonso, Jorge Andrés Sarmiento-Rojas   +2 more
doaj   +1 more source

Structural Credit Risk Models with Subordinated Processes

Journal of Applied Mathematics, 2013
We discuss structural models based on Merton's framework. First, we observe that the classical assumptions of the Merton model are generally rejected.
Martin Gurny, Sergio Ortobelli Lozza, Rosella Giacometti   +2 more
doaj   +1 more source

Model-Checking Hierarchical Structures [PDF]

20th Annual IEEE Symposium on Logic in Computer Science (LICS' 05), 2006
Hierarchical graph definitions allow a modular description of graphs using modules for the specification of repeated substructures. Beside this modularity, hierarchical graph definitions also allow to specify graphs of exponential size using polynomial size descriptions.
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Complex order-parameter phase-field models derived from structural phase-field-crystal models

, 2013
The phase-field-crystal (PFC) modeling paradigm is rapidly emerging as the model of choice when investigating materials phenomena with atomistic scale effects over diffusive time scales.
Huang, Zhi-Feng, Ofori-Opoku, Nana, Provatas, Nikolas, Stolle, Jonathan   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural Models for Cytochrome P450�Mediated Catalysis

The Scientific World Journal, 2003
This review focuses on the structural models for cytochrome P450 that are improving our knowledge and understanding of the P450 catalytic cycle, and the way in which substrates bind to the enzyme leading to catalytic conversion and subsequent formation ...
David F.V. Lewis
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source