Results 71 to 80 of about 27,750,649 (274)

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

open access: yesFEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado   +4 more
wiley   +1 more source

Assessing Mathematics Teachers’ Dispositions

open access: yesJournal of Business and Social Review in Emerging Economies, 2020
The study was aimed at comparison mathematics teacher’s dispositions at secondary level. The research was conducted to distinguish the difference of disposition among teachers on male and female basis as well as on their academic qualification base.
Khadijah Batool   +2 more
doaj   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Influence of Reynolds number on theoretical models for trailing vortices [PDF]

open access: yes, 2015
We conduct direct numerical simulations for a NACA0012 airfoil at Reynolds numbers (Re) ranging from 300 to 7000 to determine the wake behavior behind this wing profile. We characterize the structure of the wing-tip vortex, finding a reasonable agreement
Del-Pino-Peñas, Carlos Manuel   +4 more
core  

Theoretical Models for Producing Circularly Polarized Radiation in Extragalactic Radio Sources

open access: yes, 2003
We discuss the production of circular polarization in compact radio sources both by the intrinsic mechanism and by Faraday conversion. We pay particular attention to the magnetic field structure, considering partially ordered fiel ds and Laing sheets ...
Homan, Daniel C., Wardle, John F. C.
core   +1 more source

Long-Term Scintillation Studies of Pulsars: III. Testing Theoretical Models of Refractive Scintillation [PDF]

open access: yes, 1998
Refractive interstellar scintillation (RISS) is thought to be the cause behind a variety of phenomena seen at radio wavelengths in pulsars and compact radio sources.
Bhat, N. D. Ramesh   +2 more
core   +2 more sources

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

O diagrama V como ferramenta de integração analítica de conhecimentos teórico-conceituais e metodológicos na saúde

open access: yesRevista Gaúcha de Enfermagem, 2018
Resumo OBJETIVO Produzir uma reflexão sobre a capacidade do diagrama V de integrar os conhecimentos teóricos-conceituais e metodológicos obtidos de sistemas, modelos e teorias complexas e não explicitamente identificáveis.
Marcos Antônio Gomes Brandão   +4 more
doaj   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

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