Results 21 to 30 of about 4,986,787 (248)
Non-model model organisms [PDF]
BMC Biology, 2017 Model organisms are widely used in research as accessible and convenient systems to study a particular area or question in biology. Traditionally only a handful of organisms have been widely studied, but modern research tools are enabling researchers to extend the set of model organisms to include less-studied and more unusual systems.Russell, James J, Theriot, Julie A, Sood, Pranidhi, Marshall, Wallace F, Landweber, Laura F, Fritz-Laylin, Lillian, Polka, Jessica K, Oliferenko, Snezhana, Gerbich, Therese, Gladfelter, Amy, Umen, James, Bezanilla, Magdalena, Lancaster, Madeline A, He, Shuonan, Gibson, Matthew C, Goldstein, Bob, Tanaka, Elly M, Hu, Chi-Kuo, Brunet, Anne +18 moreopenaire +5 more sourcesControlling the uncontrolled variation in the diet induced obese mouse by microbiomic characterization
Scientific Reports, 2022 Group sizes in an animal study are calculated from estimates on variation, effect, power and significance level. Much of the variation in glucose related parameters of the diet-induced obese (DIO) mouse model is due to inter-individual variation in gut ...Valeriia Bondarenko, Cecillie Reynolds Løkke, Peter Dobrowolski, Caroline Junker Mentzel, Josué L. Castro-Mejía, Camilla Hartmann Friis Hansen, Dorte Bratbo Sørensen, Dennis Sandris Nielsen, Lukasz Krych, Axel Kornerup Hansen +9 moredoaj +1 more sourceUltrasound imaging for assessing aortic phenotypes: A preclinical tool for measuring cardiac disease model progression and therapeutic effect
WFUMB Ultrasound OpenCardiac dysfunction is a common feature of numerous diseases, ranging from metabolic disorders like Mucopolysaccharidosis Type 1 (MPS I), a.k.a. Hurler syndrome to neuromuscular disorders such as Myotonic Dystrophy type 1 (DM1).James Cao, Alex Jayyosi, Jennifer Nietupski, Giulio Tomassy, Ingeborg M. Langohr, Michelle Potter, Srinivas Rao, Dinesh S. Bangari, Xiaoyou Ying +8 moredoaj +1 more sourceInfluence of sperm cryopreservation on sperm motility and proAKAP4 concentration in mice
Reproductive Medicine and Biology, 2022 Background The protein proAKAP4 is crucial for sperm motility and has been suggested as an indicator of male fertility. We determined the relationship between proAKAP4 concentration and sperm motility parameters in mice, and investigated the effects of ...Auke Boersma, Jasmin Primus, Bettina Wagner, Veronika Broukal, Lill Andersen, Barbara Pachner, Maik Dahlhoff, Thomas Rülicke, Kerstin E. Auer +8 moredoaj +1 more sourceThe HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.Stefan Rutkowski, Michael C. Frühwald, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz‐Driever, Olaf Witt, Astrid Gnekow, Christof Kramm, Matthias Eyrich, Johannes E. A. Wolf, Hermann Müller, Carsten Friedrich, Uwe R. Kordes, Denise Obrecht‐Sturm, Petra Ketteler, Barbara von Zezschwitz, Pascal Johann, Dominik Sturm, Karoline Nemes, Stefan Schönberger, Till Milde, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, Ulrich Schüller, Arend Koch, David Capper, Martin Hasselblatt, Christian Thomas, Christian Hagel, Stefan M. Pfister, Felix Sahm, David T. W. Jones, Martin U. Schuhmann, Jürgen Krauss, Pedram Emami, Ahmed El Damaty, Rolf D. Kortmann, Rudolf Schwarz, Jürgen Debus, Mechthild Krause, Fabian Pohl, Holger Ottensmeier, Lisa Bußenius, Katja Baust, Andreas Faldum, Cecile Ronckers, Desiree Grabow, Martin Benesch, Thomas Perwein, Karin Dieckmann, Irene Slavc, Johannes Gojo, Nicolas U. Gerber, André O. von Bueren, Katrin Scheinemann, Gabriele Calaminus, Beate Timmermann, Ulrich‐Wilhelm Thomale, Martin Mynarek +59 morewiley +1 more sourceStressful Events Reported by Childhood Cancer Survivors and Community Controls From the St. Jude Lifetime (SJLIFE) Cohort: A Mixed Method Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction
Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods
Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.Megan E. Ware, Colter K. Clayton, Fang Wang, Sedigheh Mirzaei, Kyla Shelton, Tara M. Brinkman, Victoria Willard, Katianne M. Howard Sharp, Kevin Krull, Lindsay F. Schwartz, Melissa M. Hudson, Gregory T. Armstrong, Kirsten K. Ness, Rachel T. Webster +13 morewiley +1 more sourceRevisiting a quarter of a century of simian immunodeficiency virus (SIV)-associated cardiovascular diseases at the German Primate Center [PDF]
Primate Biology, 2017 Human immunodeficiency virus (HIV) comorbidities have become
clinically more important due to antiretroviral therapy. Although therapy
increases life expectancy, it does not completely suppress immune activation
and its associated complications.M. Mietsch, M. Mietsch, U. Sauermann, U. Sauermann, K. Mätz-Rensing, A. Klippert, M. Daskalaki, N. Stolte-Leeb, C. Stahl-Hennig +8 moredoaj +1 more sourceUtility of Computed Tomography Surveillance of Asymptomatic Infection in Children and Young Adults Before Allogeneic Hematopoietic Stem Cell Transplant
Pediatric Blood &Cancer, EarlyView.ABSTRACT
Asymptomatic infection poses a significant risk for children undergoing hematopoietic stem cell transplantation (HSCT). Pre‐transplant surveillance computed tomography (CT) is commonly used to identify occult infection, though its diagnostic yield remains uncertain.Tyler Obermark, Pradipta Debnath, Rama S. Ayyala, Lara A. Danziger‐Isakov, Jane Koo, Kasiani C. Myers, William R. Otto, Aki Tanimoto, Andrew T. Trout, Cara E. Morin +9 morewiley +1 more sourceUnheard and Under‐Supported: Health‐Related Quality of Life in Children, Adolescents, and Young Adults With Sickle Cell Disease
Pediatric Blood &Cancer, EarlyView.Abstract Background
Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy affecting millions of individuals worldwide. The clinical expression and psychosocial burden of SCD vary widely across geographical, cultural, and healthcare system contexts, underscoring the need for setting‐specific approaches to assessment.Desiré Fantasia, Giulia Reggiani, Elizabeth J. Maran, Maria Elisa Delle Fave, Ilaria Baido, Anna Chiara Frigo, Maria Paola Boaro, Raffaella Colombatti +7 morewiley +1 more source