Results 111 to 120 of about 878,862 (374)

DCAF12 Ubiquitin Ligase Promotes Lung Cancer Metastasis by Modulating the TRiC/CCT Chaperonin Complex

Advanced Science, EarlyView.
This study elucidates how DCAF12 facilitates non‐degradative ubiquitination to stabilize TRiC/CCT, thereby enhancing the folding capacity of chaperonins. This mechanism promotes the maturation of cytoskeletal proteins and activates key oncogenic drivers, including YAP, STAT3, and mTOR, ultimately driving metastatic progression in lung cancer.
Zhenyi Wang, Huanhuan Huang, Kaizong Huang, Xiaowen Cui, Leilei Wu, Renyu Lin, Zhe Zhao, Hua Chen, Cheng Zheng, Weilin Jin, Song Chen, Jiayan Chen, Yaping Xu, Dongping Wei   +13 more
wiley   +1 more source

Pedagogical strategies for teaching nursing theories in undergraduate students: A scoping review protocol.

PLoS ONE
From a pedagogical point of view, there is a great deal of creativity and practice in teaching conceptual models and nursing theories. However, there seems to be no synthesis of knowledge regarding the pedagogical methods used to teach them.
Aurélie Demagny-Warmoes, Paul Quindroit, Sébastien Colson   +2 more
doaj   +1 more source

Personal Health Tracking: A Paradigm Shift in the Self-Care Models in Nursing. [PDF]

JMIR Nurs, 2023
Choi S.
europepmc   +1 more source

PRÁCTICAS PROFESIONALES EN LA RELACIÓN CON LOS MODELOS DE ENFERMERÍA Y BIOMÉDICO [PDF]

, 2011
Objectives: to analyze the connections of professional practices with the nursing and biomedical models and identify the factors involved in the professional dynamics.
Mendes, João
core  

Development of Age‐ and Sex‐Specific Metabolomics‐Based Biological Ageing Clocks for 10‐Year Mortality Prediction

Advanced Science, EarlyView.
Metabolomics‐based ageing clocks developed using blood biomarkers from over 215 000 European adults, improved the prediction of 10‐year all‐cause mortality compared to traditional models. Biological age acceleration is associated with higher mortality risk, as each additional year of metabolic age corresponded to at least 8% increased risk. These tools
Lei Peng, Ruijie Xie, Bernd Holleczek, Hermann Brenner, Ben Schöttker   +4 more
wiley   +1 more source

Harnessing Large Language Models in Nursing Care Planning: Opportunities, Challenges, and Ethical Considerations. [PDF]

Cureus, 2023
Nashwan AJ, Abujaber AA.
europepmc   +1 more source

Ubc9‐Mediated SUMOylation of RPL3, an Unappreciated Mechanism against Hepatocyte Senescence by Repressing the DHX9‐p16 Axis

Advanced Science, EarlyView.
Liver aging is characterized by a decline in the expression of the SUMO‐conjugating enzyme Ubc9, resulting in reduced SUMOylation levels in hepatocytes, particularly in the case of ribosomal protein RPL3. Disruption of RPL3 SUMOylation increases its nuclear translocation. Interestingly, ribosome‐free RPL3 facilitates the recruitment of helicase DHX9 to
Hao Xie, Zhichao Gao, Xin Liu, Shiyi Zhang, Yuhan Wang, Jia Gao, Ping Qi, Lu Zhang, Jiawei Zhao, Tian Xiong, Teng Huang, Jia Song, Qilin Yu, Shu Zhang, Yanjun Liu, Ping Yang, Maryam S. Al‐Motawa, Quan Gong, Junfeng Dong, Hao Yin, Fei Sun, Shiwei Liu, Cong‐Yi Wang   +22 more
wiley   +1 more source

A peer-driven community-based supervisory model: development from an evaluation of an ethics workshop for doctoral students undertaking research with children [PDF]

, 2014
Differing doctoral supervision models currently exist. Three key conceptual supervisory models relevant to doctoral students from within the healthcare professions were identified from a literature review: the ‘functional pre-modern’ model, the ‘team ...
Hunt, Jane, Swallow, Veronica
core  

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

Advanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi, Song Wang, Yuqing Yan, Wei Chen, Yingying Cao, Dafan Chen, Wei Chen, Caiyun Ma, Xinjian Wan   +8 more
wiley   +1 more source

Instilling Diet and Exercise Confidence: Influence of Nurse Body Size [PDF]

, 2014
This paper reports a research study focused on perspective of nurse body size and how it affects confidence in a nurses’ ability to provide education on diet and exercise.
Spaulding, Erin Murdock
core   +4 more sources