Results 141 to 150 of about 202,754 (358)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Great Moderation at the Firm Level? Unconditional vs. Conditional Output Volatility [PDF]
Aggregated output in industrialized countries has become less volatile over the past decades. Whether this “Great Moderation” can be found in firm level data as well remains disputed.
Claudia M. Buch +2 more
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FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
BEYOND DICHOTOMIES: SOETANDYO WIGNJOSOEBROTO’S VISION FOR A MODERATED LEGAL PARADIGM
Mimbar HukumThis article employs a legal biography approach to review the thoughts of Indonesian legal philosopher Soetandyo Wignjosoebroto regarding the complexity and distinctiveness of this field of study, as well as the importance of moderating it.
Victor Imanuel W. Nalle
doaj +1 more source
E-moderation strategies in educational contexts
, 2012 This PowerPoint lecture, narrated by Professor Gilly Salmon, consists of 29 slides outlining e-moderating strategies in educational contexts centred around the 5-stage model. It also touches upon the use of e-tivities (length 21:30).
G Salmon +1 more
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Analysis of moderation practices in a large STEM-focused faculty
, 2014 Moderation of assessment constitutes a crucial element of the learning and teaching process at the university. Yet, despite its importance, many academics have confusing beliefs and attitudes towards moderation practices, processes and procedures.
Czaplinski, Iwona +7 more
core +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Indeterminate Equilibria in New Keynesian DSGE Model: An Application to the US Great Moderation
This paper tests “Bad Policy” Hypothesis which refers to the Great Moderation in the US. We examine this hypothesis by simulating model based impulse response functions for the both pre-Volcker period and post 1982 period.
Erdemlioglu, Deniz M, Xiao, Wei
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Interpreting the Great Moderation: Changes in the Volatility of Economic Activity at the Macro and Micro Levels [PDF]
We review evidence on the Great Moderation in conjunction with evidence about volatility trends at the micro level. We combine the two types of evidence to develop a tentative story for important components of the aggregate volatility decline and its ...
James A. Kahn, Steven J. Davis
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