Results 121 to 130 of about 241,852 (360)

Moderating Effects of Cortisol on Neural-Cognitive Association in Cognitively Normal Elderly Subjects

open access: yesFrontiers in Aging Neuroscience, 2017
Cortisol homeostasis is important for healthy brain and cognitive aging. The aim of the current study is to investigate the role of serum cortisol levels in the relationship between regional brain volumes and cognitive processing speed in a group of ...
Way K. W. Lau   +9 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Inventory Mistakes and the Great Moderation [PDF]

open access: yes
Why did the volatility of U.S. real GDP decline by more than the volatility of final sales with the Great Moderation in the mid-1980s? One possible explanation is that firms shifted their inventory behaviour towards a greater emphasis on production ...
Singh, Aarti, Morley, James
core  

Journalistic counter-voices in comment sections: Patterns, determinants, and potential consequences of interactive moderation of uncivil user comments [PDF]

open access: yes, 2018
Incivility in online user discussions is discussed as a significant challenge for democratic societies. Interactive journalistic moderation is seen as a promising strategy to deal with and prevent online incivility.
Bormann, Marike   +3 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Globalisation effect on inflation in the great moderation era: new evidence from G10 countries [PDF]

open access: yes
The effect of globalisation on inflation is modelled and simulated for ten countries from G10 during the Great Moderation period. The results are supportive of the globalisation hypothesis.
He, Xinhua, Qin, Duo
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

The not-so-great moderation? Evidence on changing volatility from Australian regions [PDF]

open access: yes
In this paper we examine Australian data on national and regional employment numbers, focusing in particular on whether there have been common national and regional changes in the volatility of employment.
David Shepherd, Robert Dixon
core  

Implementation of Home-Schooling: Parents’ Practices and Processes

open access: yesEducation Sciences
With increasing numbers of parents choosing to home-school their child, currently there is very limited information about how this is implemented. Utilizing the recently developed Parents’ Perceptions of Home-Schooling scale (PPHS), a survey of 93 home ...
Chris Forlin, Dianne Chambers
doaj   +1 more source

Strategic fit and strategic drift in Jordanian pharmaceutical manufacturing: The moderating role of environmental factors [PDF]

open access: yesProblems and Perspectives in Management
Type of the article: Research Article AbstractThis study aims to investigate the relationship between strategic fit and strategic drift in Jordanian pharmaceutical manufacturing and tests whether environmental factors moderate this relationship ...
Ihab Ignaim   +2 more
doaj   +1 more source

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