Results 111 to 120 of about 202,754 (358)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
This study delves into the philosophical insights of Muhammad Iqbal regarding the interaction between humanity, moderation, and technology in the digital age.
Hero Gefthi Firnando
doaj +1 more source
Assessment of group work in initial teacher education and training
This study records findings of a study carried out in a group of 100 students at a South African university. This study examines the group’s assignments as a way of gathering evidence about pre-service teachers’ achievements in the process of education ...
Mamsi Ethel Khuzwayo
doaj +1 more source
Do expectations matter? The Great Moderation revisited [PDF]
We examine the role of expectations in the Great Moderation episode. We derive theoretical restrictions in a New-Keynesian model and test them using measures of expectations obtained from survey data, the Greenbook and bond markets.
Luca Gambetti, Fabio Canova
core
Assessment moderation in an Australian context: Processes,\ud practices, and challenges
Moderation is a quality assurance process that plays a central role in the teaching, learning, and assessment cycle in higher education. While there is a growing body of research globally on teaching,learning, and, to a lesser degree, assessment in ...
Lloyd, Margaret +2 more
core +1 more source
Journalistic counter-voices in comment sections: Patterns, determinants, and potential consequences of interactive moderation of uncivil user comments [PDF]
Incivility in online user discussions is discussed as a significant challenge for democratic societies. Interactive journalistic moderation is seen as a promising strategy to deal with and prevent online incivility.
Bormann, Marike +3 more
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Content Moderation and Advertising in Social Media Platforms
We study the incentive of an ad‐funded social media platform to curb the presence of unsafe content that entails reputational risk to advertisers. We identify conditions for the platform not to moderate unsafe content and demonstrate how the optimal ...
Leonardo Madio, M. Quinn
semanticscholar +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Explaining the Great Moderation: it is not the shocks [PDF]
This paper shows that the explanation of the decline in the volatility of GDP growth since the mid-eighties is not the decline in the volatility of exogenous shocks but rather a change in their propagation mechanism.
Lenza, Michele +2 more
core

