Results 81 to 90 of about 3,795,820 (304)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Bootstrap prediction regions for daily curves of electricity demand and price using functional data
The aim of this paper is to compute one-day-ahead prediction regions for daily curves of electricity demand and price. Three model-based procedures to construct general prediction regions are proposed, all of them using bootstrap algorithms.
Rebeca Peláez +2 more
doaj +1 more source
Method of proportioning the cement-water ratio of steam-cured concrete
The article presents the results of experimental studies that made it possible to substantiate the calculated dependences of the steam-cured concrete strength and the required values of the cement-water ratio (C/W) to ensure the specified strength values.
Leonid Dvorkin, Vadim Zhitkovsky
doaj +1 more source
We generalize the Weinstein-Moser theorem on the existence of nonlinear normal modes near an equilibrium in a Hamiltonian system to a theorem on the existence of relative perodic orbits near a relative equilibrium in a Hamiltonian system with continuous ...
Arms +15 more
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Failure of oil pipeline transport infrastructure in Nigeria’s coastal ecosystem has continued to pose serious environmental problems with consequent economic effects.
Nwokedi Theophilus Chinonyerem +1 more
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
This paper aims to discuss the real and potential outcomes of Demand Responsive Transports (DRT). Those services allow to care for new mobilities that induce complex temporalities.
Elodie Castex, Didier Josselin
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

