Results 91 to 100 of about 9,581,482 (296)

Nonlinear Dynamical Analysis for a Plain Bearing

Advances in Mechanical Engineering, 2014
This paper investigates the nonlinear dynamic behavior for a plain classic bearing (fluid bearing) lubricated by a non-Newtonian fluid of a turbo machine rotating with high speed; this type of fluid contains additives viscosity (couple-stress fluid film).
Ali Belhamra, Ouafa Meramria, Khalil Kahine, Fadi Haj Chehade   +3 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

SIZE EFFECT ON THE STATIC PULL-IN INSTABILITY OF THE ELECT ROSTATICALLY ACTUATED CANTILEVER MICRO-BEAMS

Jixie qiangdu, 2018
The static pull-in instability of the electrostatically actuated cantilever micro-beams incorporating Casimir force was investigated based on the modified couple stress theory.
LU Fei, KONG ShengLi, YUAN YanQi
doaj  

Study of MHD on porous flat and curved circular plate lubricated with couple stress fluid-a slip velocity model

Results in Engineering
The current study achieved to explore novel of curved circular and porous flat plate under the existence of MHD and slip velocity. The gap between the plates is filled with conducting non-Newtonian lubricant as a couple stress fluids.
Umadevi Devani, Jagadish Patil, S. Bilal, B.N. Hanumagowda, V.B. Trimbak, JagadishV. Tawade, Nodira Nazarova, Manish Gupta   +7 more
doaj   +1 more source

Analysis of Size-Dependent Linear Static Bending, Buckling, and Free Vibration Based on a Modified Couple Stress Theory. [PDF]

Materials (Basel), 2022
Tang F, He S, Shi S, Xue S, Dong F, Liu S.   +5 more
europepmc   +1 more source

Size dependent vibro-buckling of rotating beam based on modified couple stress theory

, 2016
Micro-electro-mechanical and nano-electro-mechanical machines such as micro/nano pumps use a rotating beam as their energy transmission part. For such devices, dynamics behavior of a low scale tangentially loaded rotating beam is so important. Therefore,
Ilkhani, M.R., Hosseini-Hashemi, SH.
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Bending in Nanoplates [PDF]

Nanoscale and Advanced Materials
This research explores the flexural properties of four different nanoplate designs employing the Modified Couple Stress Theory (MCST). This approach utilizes a solitary length scale factor to represent nanoscale size influences effectively.
Majid Eskandari Shahraki, Alireza Asadolahei, Payam Mohammadi, Mohsen Heydari Beni, Jafar Eskandari Jam   +4 more
doaj   +1 more source

Size-Dependent Buckling and Post-Buckling Analysis of the Functionally Graded Thin Plate Al-Cu Material Based on a Modified Couple Stress Theory. [PDF]

Nanomaterials (Basel), 2022
Tang F, Dong F, Guo Y, Shi S, Jiang J, Liu S.   +5 more
europepmc   +1 more source