Results 81 to 90 of about 9,581,482 (296)

Free vibration of angle-ply laminated micro-plates using isogeometric analysis and modified couple stress theory

, 2020
Based on new modified couple stress and isogeometric analysis, this paper presents a non-classical Reissner-Mindlin plate theory model for free vibration of angle-ply laminate micro-plate. This study extends the new modified couple stress for complicated
Le, Thanh Cuong, Khatir, Samir, Abdel Wahab, Magd   +2 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Geometrically nonlinear isogeometric analysis of functionally graded microplates with the modified couple stress theory [PDF]

, 2017
In this study, a new and efficient computational approach based on isogeometric analysis (IGA) and refined plate theory (RPT) is proposed for the geometrically nonlinear analysis of functionally graded (FG) microplates.
Nguyen Xuan, H., Atroshchenko, Elena, Nguyen, Hoang, Vo, Thuc, Nguyen, Hoang X, Elena Atroshchenko, Vo, Thuc P., H. Nguyen-Xuan, Nguyen-Xuan, Hung, Thuc P. Vo, Hoang X. Nguyen   +10 more
core   +2 more sources

Flexural Vibration of an Atomic Force Microscope Cantilever Based on Modified Couple Stress Theory

, 2015
This paper is concerned with the flexural vibration of an atomic force microscope (AFM) cantilever. The cantilever problem is formulated on the basis of the modified couple stress theory and the Timoshenko beam theory.
Ke, Liao-Liang., Wang, Yue-Sheng., Liang, Li-Na, Yang, Jie., Kitipornchai, Sritawat.   +4 more
core   +1 more source

Static and vibration analysis of functionally graded beams using refined shear deformation theory [PDF]

, 2013
Static and vibration analysis of functionally graded beams using refined shear deformation theory is presented. The developed theory, which does not require shear correction factor, accounts for shear deformation effect and coupling coming from the ...
Thai, Huu-Tai, Inam, Fawad, Vo, Thuc, Nguyen, Trung-Kien   +3 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

An Accurate Study on Capacitive Microphone with Circular Diaphragm Using a Higher Order Elasticity Theory

Latin American Journal of Solids and Structures
This study has been undertaken to investigate the mechanical behavior of the capacitive microphone with clamped circular diaphragm using modified couple stress theory in comparison to the classical one.
Shakiba Dowlati, Ghader Rezazadeh, Saeid Afrang, Mehrdad Sheykhlou, Aysan Madan Pasandi   +4 more
doaj   +1 more source

Size Dependent Pull-in Phenomena in Electro-Statically Actuated Micro-Beam Based on the Modified Couple Stress Theory

, 2011
A modified continuum model of electro-statically actuated micro-beam is presented based on the modified couple stress theory. The new model contains a material length scale parameter and can capture the size effect, unlike the classical Bernoulli-Euler ...
Bing Lei Wang, Jun Feng Zhao, Shen Jie Zhou   +2 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source