Results 91 to 100 of about 9,718,541 (278)

Optimal and Pressure-Independent $$L^2$$ L 2 Velocity Error Estimates for a Modified Crouzeix-Raviart Element with BDM Reconstructions

, 2014
Nearly all inf-sup stable mixed finite elements for the incompressible Stokes equations relax the divergence constraint. The price to pay is that a-priori estimates for the velocity error become pressure-dependent, while divergence-free mixed finite ...
Christian Brennecke, Linke, Alexander, Merdon, Christian, Schöberl, Joachim, Brennecke, Christian, Alexander Linke, Joachim Schöberl, Christian Merdon   +7 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Adaptive minimum bit-error-rate filtering

, 2004
Adaptive filtering has traditionally been developed based on the minimum mean square error (MMSE) principle and has found ever-increasing applications in communications. The paper develops adaptive filtering based on an alternative minimum bit error rate
Chen, S.
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Non-linear height-diameter models for oriental beech (Fagus orientalis Lipsky) in the Hyrcanian forests, Iran

Biotechnologie, Agronomie, Société et Environnement, 2013
The relationship between tree height and diameter is an important element in growth and yield models, in carbon budget and timber volume models, and in the description of stand dynamics. Six non-linear growth functions (i.e.
Ahmadi, K., Alavi, SJ., Kouchaksaraei, MT., Aertsen, W.   +3 more
doaj  

Analysis and Compensation of Kinematic and Hysteresis Errors in Industrial Robots

IEEE Access
Industrial robots are extensively utilized in handling, assembly, and welding tasks owing to their expansive workspace, scalability, flexibility, and cost-effectiveness.
Wei He, Kai Guo, Jie Sun
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Error analysis for stochastic gradient optimization schemes using modified equations

We consider a class of stochastic gradient optimization schemes. Assuming that the objective function is strongly convex, we prove weak error estimates which are uniform in time for the error between the solution of the numerical scheme, and the ...
Dambrine, Marc, En-Nebbazi, Nassim, Bréhier, Charles-Édouard   +2 more
core   +3 more sources