Results 101 to 110 of about 9,718,541 (278)
Efficient Design of Digital FIR Differentiator using $L_1$-Method [PDF]
In this paper, an efficient design of FIR digital differentiator using the $L_1$-optimality criterion is proposed. We present a technique based on the modified Newton method to solve the design problem so that the optimal differentiator coefficients are ...
A. Aggarwal +3 more
doaj
EXISTENCE AND UNIQUENESS OF THE P-GENERALIZED MODIFIED ERROR FUNCTION
In this article, we de ne a p-generalized modi ed error function as the solution to a non-linear ordinary di erential equation of second order, with a Robin type boundary condition at x = 0. We prove existence and uniqueness of a non-negative C1 solution by using a xed point argument.
openaire +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Enhanced SAR Image Formation via a Modified Omega-K Algorithm
In this paper, a high-resolution synthetic aperture radar (SAR) focusing technique is proposed based on a modified omega-K algorithm in case of long synthetic aperture time. The proposed algorithm includes three stages.
Min-Seok Kang
doaj +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
The Logistic Regression Model with a Modified Weight Function in Survival Analysis [PDF]
Most of the Ridge regression estimators can only achieve one property or the other, namely, variance reduction, bias reduction or reduced Mean Square Error.
Nduka, E.C, Ogoke, U.P, Nja, M.E
core +1 more source
Phenomenological and physical-based constitutive models for the Cr17Mn17Mo3NiN low nickel stainless steel were developed based on the true stress–strain curves acquired from isothermal uniaxial compression tests.
Gun Song Jang, Kyong Ho Sim
doaj +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source

