Results 91 to 100 of about 1,727,557 (286)

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

open access: yesAdvanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang   +10 more
wiley   +1 more source

Elimination of proinflammatory cytokines in pediatric cardiac surgery: analysis of ultrafiltration method and filter type.

open access: yes, 2004
ObjectiveThis study was undertaken to assess whether different filter types or ultrafiltration methods influence inflammatory markers in pediatric cardiac surgery.MethodsForty-one children younger than 5 years were prospectively randomized to groups A ...
Pfammatter JP   +8 more
core   +1 more source

Enhanced Separation Performance of Polyimide Ultrafiltration Membranes Embedded with Deep Eutectic Solvent-Coated Nanodiamonds

open access: yes, 2023
Polymer materials such as polyimide can be used to make ultrafiltration membranes, but the hydrophobic surface is susceptible to contamination, resulting in a decline in its antifouling performance.
Shencheng Pan (6793238)   +7 more
core   +1 more source

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou   +14 more
wiley   +1 more source

Polyvinylidene Fluoride Membrane Modified by PEG Additive for Tofu Industrial Wastewater Treatment

open access: yesChemEngineering
This study investigates the enhancement of polyvinylidene fluoride (PVDF) membranes with polyethylene glycol (PEG) to improve their efficacy in treating tofu wastewater through the ultrafiltration (UF) process.
Sutrasno Kartohardjono   +4 more
doaj   +1 more source

Effect of combined conventional ultrafiltration and modified ultrafiltration on serum interleukin-6 and TNF-α levels in pediatric cardiac surgery patients [PDF]

open access: yes, 2019
Background: Water retention occurs in most of the congenital heart surgery patients, especially in pediatrics. Ultrafiltration excretes water, electrolytes, many free radicals and inflammatory mediators.
Dabbagh, A.   +5 more
core   +1 more source

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

open access: yesAdvanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou   +12 more
wiley   +1 more source

Modified Ultrafiltration Technique in Valvular Heart Surgery: A Case Series

open access: yesBali Journal of Anesthesiology
Application of cardiopulmonary bypass (CPB) in cardiac surgery may cause systemic inflammatory reactions, possibly causing clinical sequelae and multiple organ failures such as systolic or diastolic dysfunction, regional or global left ventricle or right
Made Ryan Kharmayani   +3 more
doaj   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

open access: yesAdvanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang   +9 more
wiley   +1 more source

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