Results 81 to 90 of about 1,623,043 (289)

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

Polymer Nanocomposite Ultrafiltration Membranes: The Influence of Polymeric Additive, Dispersion Quality and Particle Modification on the Integration of Zinc Oxide Nanoparticles into Polyvinylidene Difluoride Membranes

Membranes, 2020
This study aims to improve the understanding of the influence of metal oxide nanofillers on polyvinylidene difluoride (PVDF) ultrafiltration membranes. Zinc oxide nanoparticles were chosen as the model filler material.
Thorsten van den Berg, Mathias Ulbricht
doaj   +1 more source

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source

Assessment of modified ultrafiltration hemodynamic impact by pressure recording analytical method during pediatric cardiac surgery

, 2013
Objective:: Modified ultrafiltration is commonly used in pediatric cardiac surgery. Although its clinical benefits are currently debated, modified ultrafiltration has proved to improve mean arterial pressure in the first postoperative hours.
Netto, Roberta, Favia, Isabella, COGO, Paola, De Razza, Francesca, Ricci, Zaccaria, Carotti, Adriano, Polito, Angelo   +6 more
core   +1 more source

METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer

Advanced Science, EarlyView.
GC cells enhance glutamine accumulation by upregulating SLC1A5 expression. This upregulation not only boosts GC cell proliferation, but also outcompetes CD8+ T cells for glutamine and suppresses their antitumor immunity. Mechanistically, METTL7A deficiency in GC induces SLC1A5 overexpression via an m6A‐dependent pathway and N‐glycosylation ...
Mingjun Sun, Shuwei Dang, Dazhi Zhou, Lixian Ding, Xun Sun, Wei Suo, Jirui Niu, Qingzhu Yang, Zhicheng Zhang, Yanyan Sun, Jinxing Li, Zhongsheng Chen, Tao Ban, Yingji Wang, Tianzhu Li, Ming Liu, Guodong Li   +16 more
wiley   +1 more source

Integrated approach to elevating PES membrane performance with a dynamic silica and chitosan additive duo

South African Journal of Chemical Engineering
Membrane fouling, low permeate flux, and the trade-off between flux and solute rejection remain pressing challenges in ultrafiltration processes, often compromising efficiency and selectivity.
Umi Fathanah, Cut Meurah Rosnelly, Zuhra Zuhra, Syawaliah Muchtar, Fachrul Razi, Wahyu Rinaldi, Yanna Syamsuddin   +6 more
doaj   +1 more source

Performance of Layer-by-Layer-Modified Multibore^® Ultrafiltration Capillary Membranes for Salt Retention and Removal of Antibiotic Resistance Genes

Membranes, 2020
Polyether sulfone Multibore® ultrafiltration membranes were modified using polyelectrolyte multilayers via the layer-by-layer (LbL) technique in order to increase their rejection capabilities towards salts and antibiotic resistance genes.
Robert Niestroj-Pahl, Lara Stelmaszyk, Ibrahim M. A. ElSherbiny, Hussein Abuelgasim, Michaela Krug, Christian Staaks, Greta Birkholz, Harald Horn, Tian Li, Bingzhi Dong, Lars Dähne, Andreas Tiehm, Stefan Panglisch   +12 more
doaj   +1 more source

Molecular‐Level Pore Engineering for Precise Separation via Active Solvent‐Mediated Interfacial Polymerization

Advanced Science, EarlyView.
We demonstrate that microemulsion solvents can actively template molecular‐level pores within selective layer during interfacial polymerization. By creating localized quasi‐homogeneous polymerization zones, the membrane achieved a 7.1‐fold enhancement in water permeance with increased selectivity.
Feng Li, R. M. G. Rajapakse, Yuxin Mou, Deyin Hou, Min Yang   +4 more
wiley   +1 more source

Modified Ultrafiltration in Pediatric Heart Surgery

, 2018
Modified ultrafiltration techniques in ...
Padalino M, Stellin G
core  

Use of the Quest Myocardial Protection System” (MPS) for Modified Ultrafiltration During Pediatric Cardiac Surgery

, 2005
Modified ultrafiltration generally is considered a standard of care for treating children undergoing cardiopulmonary bypass for congenital heat surgery. Different methods, incorporating a variety of devices and technologies, have been described.
James D. Murdock, Myra H. Klayman, Bianca R. Yen, Cody C. Trowbridge, Alfred H. Stammers, Christian L. Gilbert   +5 more
core   +1 more source