Results 81 to 90 of about 1,727,557 (286)

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol‐Mediated Cellular Uptake for miRNA Nano‐Drugs

Advanced Science, EarlyView.
The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang, Hui Wang, Hao Zhang, Zhenkuan Cao, Zehui Liu, Siying Li, Hongda Wang, Yuping Shan   +7 more
wiley   +1 more source

Polymer Nanocomposite Ultrafiltration Membranes: The Influence of Polymeric Additive, Dispersion Quality and Particle Modification on the Integration of Zinc Oxide Nanoparticles into Polyvinylidene Difluoride Membranes

Membranes, 2020
This study aims to improve the understanding of the influence of metal oxide nanofillers on polyvinylidene difluoride (PVDF) ultrafiltration membranes. Zinc oxide nanoparticles were chosen as the model filler material.
Thorsten van den Berg, Mathias Ulbricht
doaj   +1 more source

A Dual‐Mode In Situ EV‐miRNA Profiling Platform for Machine‐Learning‐Assisted Gastric Cancer Liquid Biopsy

Advanced Science, EarlyView.
An in situ dual‐mode platform integrates fusogenic liposomes with localized autocatalytic DNA circuits for plasma‐derived extracellular vesicle microRNA analysis. Following membrane fusion, target miRNAs trigger feedback‐assisted LECHA amplification inside intact vesicles, generating fluorescence and electrochemical outputs. Machine learning integrates
Wenbin Li, Rui Fan, Kun Xie, Jiehua Zhong, Yitong Zhu, Tingting Ji, Yuanyuan Qin, Shijin Peng, Yu Zhang, Yuhang Guo, Tiange Zhang, Chunchen Liu, Bo Li, Lei Zheng, Ye Zhang, Xiaohui Yan   +15 more
wiley   +1 more source

Integrated approach to elevating PES membrane performance with a dynamic silica and chitosan additive duo

South African Journal of Chemical Engineering
Membrane fouling, low permeate flux, and the trade-off between flux and solute rejection remain pressing challenges in ultrafiltration processes, often compromising efficiency and selectivity.
Umi Fathanah, Cut Meurah Rosnelly, Zuhra Zuhra, Syawaliah Muchtar, Fachrul Razi, Wahyu Rinaldi, Yanna Syamsuddin   +6 more
doaj   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Performance of Layer-by-Layer-Modified Multibore^® Ultrafiltration Capillary Membranes for Salt Retention and Removal of Antibiotic Resistance Genes

Membranes, 2020
Polyether sulfone Multibore® ultrafiltration membranes were modified using polyelectrolyte multilayers via the layer-by-layer (LbL) technique in order to increase their rejection capabilities towards salts and antibiotic resistance genes.
Robert Niestroj-Pahl, Lara Stelmaszyk, Ibrahim M. A. ElSherbiny, Hussein Abuelgasim, Michaela Krug, Christian Staaks, Greta Birkholz, Harald Horn, Tian Li, Bingzhi Dong, Lars Dähne, Andreas Tiehm, Stefan Panglisch   +12 more
doaj   +1 more source

A high-efficiency ultrafiltration nanofibrous membrane with remarkable antifouling and antibacterial ability

, 2018
The amphiphilic multi-arm f-PPTA modified ultrafiltration membrane exhibited super-high permeate flux, and remarkable antifouling ability and antibacterial activity.
Xuan-ang Du, Shaokun Song, Yanyun Ju, Zhuo Chen, Yang Liu, Lijie Dong   +5 more
core   +1 more source

Ultrafiltration membranes modified by PSS deposition and plasma treatment for Cr(VI) removal [PDF]

, 2019
Ultrafiltration, UF, membranes positively-charged on a substrate of polyvinylidene fluoride, PVDF, have been modified by the deposition of a layer of poly(styrenesulfonate), PSS, which is negatively charged.
Sandoval Olvera, Ivette G., Palacio Martínez, Laura, Prádanos del Pico, Pedro Lourdes, Ávila Rodríguez, Mario, González Muñoz, Pilar, Hernández Giménez, Antonio   +5 more
core   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Effect of hydrophilic / hydrophobic fractions of Natural Organic Matter on irreversible fouling of membranes [PDF]

, 2009
Natural organic matter (NOM) has been identified as a major factor affecting membrane processes performances, but its impact is difficult to quantify from global parameters such as organic carbon content.
Jefferson, Bruce, Bessiere, Yolaine, Bacchin, Patrice, Goslan, Emma, Y. Bessiere, B. Jefferson, P. Bacchin, E. Goslan   +7 more
core   +1 more source