Results 61 to 70 of about 1,727,557 (286)

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

A prospective randomized study comparing volume-standardized modified and conventional ultrafiltration in pediatric cardiac surgery

, 2001
Background: Modified ultrafiltration has been touted as superior to conventional ultrafiltration for attenuating the consequences of hemodilution after cardiac surgery with cardiopulmonary bypass in children.
Chen, Mark J., Thompson, LeNardo D., Parry, Andrew J., Petrossian, Ed, Findlay, Pauline, Hanley, Frank L., McElhinney, Doff B., Reddy, V.Mohan, Minami, Mariko, Miller-Hance, Wanda   +9 more
core   +1 more source

MetaboSense: An Integrated Quantum Dot‐Mediated Aptamer Assay and Modular Microfluidic Platform for Continuous In‐Line Monitoring of Lung Metabolism During Ex Vivo Perfusion

Advanced Science, EarlyView.
MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant, Pouyan Keshavarz Motamed, Thomas Borrillo, Lielle Ronen, Gabriel Siebiger, Guillermo Garza, Hesam Abouali, Md Fahim Al Fattah, Ines Jaber, Dayan Ban, Marcelo Cypel, Mingyao Liu, Shaf Keshavjee, Andrew T. Sage, Mahla Poudineh   +14 more
wiley   +1 more source

Dual-modified PVDF ultrafiltration membranes via semi-interpenetrating polymer network construction and PANI surface polymerization

Journal of Saudi Chemical Society
To enhance the filtration and antifouling properties of polyvinylidene fluoride (PVDF) ultrafiltration membranes, a dual modification strategy was implemented.
Jie Zhang, Yiming Han, Mingzhong Wu, Da Zhang, Wenjun Zhao, Chengyang Shi, Jianwei Xu, Hongyun Cui   +7 more
doaj   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

Advanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang, Xiaoyan Li, Xiao Xu, Kelun Zhang, Fengjiao Yu, Zhen Shang, Nailong Pan, Junlin Lv, Yiwei Xu, Yan Tang, Liang Zhang, Xiaotong Li, Taoyi Wang, Jing Tao, Jiaxu Song, Mengyu Zhang, Xin Ma, Dan Han, Xiaoying Kong, Wenhua Xu   +19 more
wiley   +1 more source

Modification of Polysulfone Ultrafiltration Membranes via Addition of Anionic Polyelectrolyte Based on Acrylamide and Sodium Acrylate to the Coagulation Bath to Improve Antifouling Performance in Water Treatment

Membranes, 2020
Surface modification of polysulfone ultrafiltration membranes was performed via addition of an anionic polymer flocculant based on acrylamide and sodium acrylate (PASA) to the coagulation bath upon membrane preparation by non-solvent induced phase ...
Tatiana V. Plisko, Alexandr V. Bildyukevich, Katsiaryna S. Burts, Tatiana A. Hliavitskaya, Anastasia V. Penkova, Sergey S. Ermakov, Mathias Ulbricht   +6 more
doaj   +1 more source

Preparation, characterization, and photocatalytic performance of polyvinylidene fluoride membrane modified with TiO2-C hybrid aerogels [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2016
TiO2-C hybrid aerogels containing submicrometer anatase and carbon nanoparticles were prepared with TiCl4 and resorcinol-furfural. A modified polyvinylidene fluoride (PVDF) ultrafiltration membrane was prepared through phase inversion after ...
Li Jun, Liu Jing, Bi Dongsu, Guo Xiaopin, Wang Peng   +4 more
doaj   +1 more source

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

Advanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang, Shijie He, Yuheng Chang, Sheng Mao, Jianan Canal Li, Binbin Chen, Hongxun Gao, Mingchun Xu, Chenxu Liu, Yajie Wang   +9 more
wiley   +1 more source

Properties of polyethersulfone ultrafiltration membranes modified with polyethylene glycols

Polymer Engineering & Science, 2013
Polyethersulfone ultrafiltration membranes have been prepared using polyethylene glycols (PEGs) of 400, 1000, and 10,000 gmol, as additive with dimethylacetamide as solvent. Infrared analysis proves that PEG leaves almost completely the surface of the membranes after 24 h of water immersion.
Méndez, Mercedes Liliana, Romero, Analía Irma, Rajal, Verónica Beatriz, Castro Vidaurre, Elza Fani, Calvo, Jose Ignacio, Palacio, Laura, Hernandez, Antonio Maria   +6 more
openaire   +3 more sources