Contemporary Applications of Chemical Libraries for Drug Discovery and Methods for Their Synthesis
Screening of chemical libraries has over the past decades become a cornerstone of drug discovery. Today, a broad range of chemical libraries exist but they are often not well described in terms of diversity. This review describes current efforts which aim to visualize chemical diversity in compound collections and discuss current trends in synthetic ...
Tobias N. Hansen, Nils J. V. Hansen
wiley +1 more source
Optimization of Tangential Flow Filtration for High-Yield, Scalable Downstream Processing of Adeno-Associated Virus. [PDF]
Cardoso S, Bollmann F, Tappe A.
europepmc +1 more source
Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein
The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley +4 more
wiley +1 more source
Recent Advances in Membrane Filtration and Purification Technologies. [PDF]
Khalil AM.
europepmc +1 more source
Diagnostic performance of a 250-ml net ultrafiltration challenge to identify risk of preload-dependence in critically ill patients undergoing continuous renal replacement therapy: a randomized, cross-over trial. [PDF]
Biscarrat C +7 more
europepmc +1 more source
Drinking Water Treatment Using PES/ZnO Mixed Matrix Membranes: Enhanced Antifouling Performance and Rejection at Low Nanoparticle Loadings. [PDF]
Silva VB +5 more
europepmc +1 more source
Membrane Separation Techniques: Advances, Challenges, and Future Avenues. [PDF]
Ho CD.
europepmc +1 more source
Walnut glutelin antibacterial peptides target <i>Staphylococcus aureus</i> through metabolic pathway and novel antibacterial peptides identification. [PDF]
Ma H +6 more
europepmc +1 more source
AEIOU strategy for continuous renal replacement therapy in infants <10 kg: a practical and educational framework. [PDF]
Prada Rico M +3 more
europepmc +1 more source
Efficacy of Combined Modified and Conventional Ultrafiltration During Cardiac Surgery in Children
Aggarwal NK, Das SN, Sharma G, Kiran U
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