Results 241 to 250 of about 66,987 (302)

Contemporary Applications of Chemical Libraries for Drug Discovery and Methods for Their Synthesis

open access: yesChemistryEurope, Volume 4, Issue 5, May 2026.
Screening of chemical libraries has over the past decades become a cornerstone of drug discovery. Today, a broad range of chemical libraries exist but they are often not well described in terms of diversity. This review describes current efforts which aim to visualize chemical diversity in compound collections and discuss current trends in synthetic ...
Tobias N. Hansen, Nils J. V. Hansen
wiley   +1 more source

Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein

open access: yesChemistry–Methods, Volume 6, Issue 5, May 2026.
The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley   +4 more
wiley   +1 more source

Efficacy of Combined Modified and Conventional Ultrafiltration During Cardiac Surgery in Children

open access: yesAnnals of Cardiac Anaesthesia, 2007
Aggarwal NK, Das SN, Sharma G, Kiran U
doaj  

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