Results 61 to 70 of about 2,856,616 (381)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Design and Climate-Responsiveness Performance Evaluation of an Integrated Envelope for Modular Prefabricated Buildings

open access: yesAdvances in Materials Science and Engineering, 2018
Modular prefabricated buildings effectively improve the efficiency and quality of building design and construction and represent an important trend in the development of building industrialization. However, there are still many deficiencies in the design
Junjie Li   +5 more
doaj   +1 more source

Design features of modular buildings

open access: yesThe Eurasian Scientific Journal, 2022
The paper is devoted to modular buildings as а current topic of modern construction. A significant number of studies on this topic have appeared both in Russia and abroad in last years. It is necessary to classify modular buildings and highlight their design features to systematize the research.
openaire   +1 more source

An improved lumped parameter method for building thermal modelling [PDF]

open access: yes, 2014
In this work an improved method for the simplified modelling of the thermal response of building elements has been developed based on a 5-parameter second-order lumped parameter model.
Underwood, Chris
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Economic Viability of Photovoltaic Systems Based on the Number of Floors in Modular Multi-Family Housing in Korea

open access: yesEnergies
Korea is making efforts to reduce carbon emissions from buildings and, as part of this initiative, the government is promoting the expansion of modular housing.
Seyeon Lee, Chanwoo Jung, Yonghan Ahn
doaj   +1 more source

Discrete Convex Functions on Graphs and Their Algorithmic Applications

open access: yes, 2017
The present article is an exposition of a theory of discrete convex functions on certain graph structures, developed by the author in recent years.
A Bernáth   +36 more
core   +1 more source

WETWALL - an innovative design concept for the treatment of wastewater at an urban scale [PDF]

open access: yes, 2018
Rising temperatures, increasing food demand and scarcity of water and land resources highlight the importance of promoting the sustainable expansion of agriculture to our urban environment, while preserving water resources.
Arias, Carlos Alberto   +7 more
core   +4 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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