Results 61 to 70 of about 3,824 (290)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Structural robustness of composite modular buildings: The roles of CFST columns and inter-module connections

, 2023
This paper explores the important roles of concrete filled steel tube (CFST) columns and inter-module connections on the structural robustness of composite modular buildings.
Liu, X, Swami, G, Thai, H-T
core   +1 more source

Towards an Effective Architectural Form: The Composition of Squareness and Roundness Based on Scale Proportion—Evidence from the Yingxian Wooden Pagoda

Buildings
Investigating the mathematical and geometric principles embedded in ancient classic architecture is a significant tradition in the history of architectural development.
Lu Shi, Xu Chen, Yuqian Xu, Xing Gao, Jialong Lai, Shusheng Wang   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Design features of modular buildings

The Eurasian Scientific Journal, 2022
The paper is devoted to modular buildings as а current topic of modern construction. A significant number of studies on this topic have appeared both in Russia and abroad in last years. It is necessary to classify modular buildings and highlight their design features to systematize the research.
openaire   +1 more source

Manufacturing of modular buildings: A literature review

, 2017
The recent decade has seen a growing interest in applying modular construction in high-rise buildings. However, the manufacturing of modular buildings remains slow in making technical progress and the productivity in the factory is low. The production of
Pan, Wei, Pan, M, Pan, Mi, Yang, Y, Pan, W, Yang, Yi   +5 more
core   +2 more sources

The optimal insulation thickness determined for modular buildings according to multi-criteria analysis

, 2021
The possibility of using modular buildings for residential and public needs is considered. Due to the peculiarities of technology and the use of thermal insulation materials, such structures are erected in a short time with the help of ready-made ...
Zhelykh, Vasyl, Furdas, Yurii, Yurii Furdas, Vasyl Zhelykh   +3 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Building blocks for adaptive modular sensing systems [PDF]

2007 IEEE International Conference on Systems, Man and Cybernetics, 2007
This paper describes the design and implementation of a set of building blocks for the construction of adaptive modular sensing systems. A hardware architecture is proposed which allows the development of a general set of modular components with embedded knowledge about their capabilities.
Anita Jain, Michael D. Naish
openaire   +1 more source

STUDY ON MODULAR HOUSES DESIGN

Journal of Industrial Design and Engineering Graphics, 2019
In the field of civil engineering, in the last period emerged and developed the idea of modular constructions, which is in consensus with the alert rhythm of the present times that we are going through, while responding to the requirement of economic ...
Carmen MARZA, Georgiana CORSIUC, Ana Maria GRAUR   +2 more
doaj   +4 more sources