Results 61 to 70 of about 3,439,277 (227)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

A Review on Design Considerations and Connection Techniques in Modular Composite Construction

open access: yesApplied Sciences
Precast concrete structures have become increasingly popular in the construction industry due to their ability to enhance efficiency, structural soundness, quality, and sustainability.
Manivannan Thulasirangan Lakshmidevi   +3 more
doaj   +1 more source

Multi-Performance Characterization of a Modular Wooden House

open access: yesEnergies, 2023
Although not a new concept, modular construction has been the target of increasing interest and investment in recent years. Modular wood construction systems have economic and environmental advantages, as wood is a natural and locally available raw ...
João M. P. Q. Delgado   +7 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Opportunities and Challenges in the Implementation of Modular Construction Methods for Urban Revitalization

open access: yesSustainability
The urban landscape is undergoing significant transformations due to economic shifts, urban planning initiatives, technological advancements, and sociopolitical changes. Almost 89% of the U.S.
Cansu Coskun   +5 more
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

The Study of Potential Application of Modular Construction in The Development of Indonesia’s New Capital City

open access: yesJurnal Teknik Sipil, 2022
.  The infrastructure industry is a crucial sector that significantly impacts economic growth.  In the second quarter of 2020, infrastructure was the fourth most significant contributor to Indonesia’s economy, contributing 10.56% of the total GDP ...
Oktaviani Turbaningsih   +2 more
doaj   +1 more source

Sound insulation design of modular construction housing [PDF]

open access: yes, 2007
This paper provides an insight into the acoustic issues of modular housing using the Verbus System of construction. The paper briefly summarises the history of the development of Verbus modular housing and the acoustic design considerations of the ...
Campbell, A.   +2 more
core  

The Igusa modular forms and ``the simplest'' Lorentzian Kac--Moody algebras

open access: yes, 1996
We find automorphic corrections for the Lorentzian Kac--Moody algebras with the simplest generalized Cartan matrices of rank 3: A_{1,0} = 2 0 -1 0 2 -2 -1 -2 2 and A_{1,I} = 2 -2 -1 -2 2 -1 -1 -1 2 For A_{1,0} this correction is given
Gritsenko, Valeri A.   +1 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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