Results 61 to 70 of about 369,475 (283)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Modular construction as a promising alternative for the construction of affordable and quality housing [PDF]

MATEC Web of Conferences
This study seeks to explore the fundamental characteristics of modular construction, which covers the details of design and construction processes, from production through to assembly.
Antunes Duarte R.P.B., Lúcio Válter J.G., Pinho Fernando F.S.   +2 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

An explicit Waldspurger formula for Hilbert modular forms

, 2018
We describe a construction of preimages for the Shimura map on Hilbert modular forms, and give an explicit Waldspurger type formula relating their Fourier coefficients to central values of twisted L-functions.
Sirolli, Nicolás, Tornaría, Gonzalo
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Modular Construction in the Digital Age: A Systematic Review on Smart and Sustainable Innovations

Buildings
Modular construction provides numerous benefits over traditional methods, especially when combined with digital technologies, offering a faster, safer, leaner, and more sustainable construction environment.
Diogo F. R. Parracho, Mohamed Nour El-Din, Iraj Esmaeili, Sara S. Freitas, Leonardo Rodrigues, João Poças Martins, Helena Corvacho, João M. P. Q. Delgado, Ana Sofia Guimarães   +8 more
doaj   +1 more source

Modular construction survey [PDF]

, 2003
Los sistemas modulares son procedimientos constructivos en los cuales la unidad estructural fundamental del mismo se repite de una manera regular a lo largo de todo el proyecto.
Blanco Álvarez, José Luis
core  

Geometric construction of modular functors from Conformal Field Theory

, 2006
This is the second paper in a series of papers aimed at providing a geometric construction of modular functors and topological quantum field theories from conformal field theory building on the constructions in [TUY] and [KNTY].
Bakalov B., JØRGEN ELLEGAARD ANDERSEN, KENJI UENO, Turaev V.   +3 more
core   +3 more sources

Modular construction of Boolean networks

Physica D: Nonlinear Phenomena
Boolean networks have been used in a variety of settings, as models for general complex systems as well as models of specific systems in diverse fields, such as biology, engineering, and computer science. Traditionally, their properties as dynamical systems have been studied through simulation studies, due to a lack of mathematical structure.
Matthew Wheeler, Claus Kadelka, Alan Veliz-Cuba, David Murrugarra, Reinhard Laubenbacher   +4 more
openaire   +3 more sources