Results 81 to 90 of about 3,439,277 (227)
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Inspection of intermodular connection locations for multistory modular buildings
Modular construction is a method of construction that involves prefabricating modular indoor spaces in a factory and then assembling them at the construction site.
Jae Sang Moon +3 more
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Long life, low cost ball valve, with lifted seals and cartridge type construction [PDF]
Ball valve design incorporates modular construction in easy-to-install, easy-to-replace cartridge housing, and a system of cams to lift upstream and downstream seals away from the ball during rotation.
Carriker, J. W., Fieweger, R.
core +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The traditional way of building modular devices constructive postulates the need to include in the modular device bulky non-modular unit that is running a series-parallel op-erations of modular arithmetic.
Viljan Mavlutinovich Amerbaev +3 more
doaj
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Evaluating Modular House Construction Projects: A Delphi Method Enhanced by Conversational AI
This study focuses on evaluating modular house construction projects, which is a critical segment within sustainable building practices. Despite the significant advantages of modular construction, such as enhanced resource efficiency and reduced ...
Augustinas Maceika +2 more
doaj +1 more source

