Results 51 to 60 of about 389,243 (281)

Heterotic-string amplitudes at one loop: modular graph forms and relations to open strings

open access: yesJournal of High Energy Physics, 2019
We investigate one-loop four-point scattering of non-abelian gauge bosons in heterotic string theory and identify new connections with the corresponding open-string amplitude.
Jan E. Gerken   +2 more
doaj   +1 more source

Hecke operators on Hilbert-Siegel modular forms

open access: yes, 2007
We define Hilbert-Siegel modular forms and Hecke "operators" acting on them. As with Hilbert modular forms, these linear transformations are not linear operators until we consider a direct product of spaces of modular forms (with varying groups), modulo ...
Caulk, Suzanne, Walling, Lynne H.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

D 4 modular forms

open access: yesAmerican Journal of Mathematics, 2006
In this paper, we study modular forms on two simply connected groups of type D 4 over Q. One group, G s , is a globally split group of type D 4 , viewed as the group of isotopies of the split rational octonions. The other, G c , is the isotopy group of the rational (nonsplit) octonions. We study automorphic forms on G s in analogy to the work of Gross,
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Modular A 5 symmetry for flavour model building

open access: yesJournal of High Energy Physics, 2019
In the framework of the modular symmetry approach to lepton flavour, we consider a class of theories where matter superfields transform in representations of the finite modular group Γ5 ≃ A 5.
P. P. Novichkov   +3 more
doaj   +1 more source

Are neutrino masses modular forms?

open access: yes, 2017
We explore a new class of supersymmetric models for lepton masses and mixing angles where the role of flavour symmetry is played by modular invariance.
Feruglio, Ferruccio
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Flux vacua and modularity for $\mathbb{Z}_2$ symmetric Calabi-Yau manifolds

open access: yesSciPost Physics, 2023
We find continuous families of supersymmetric flux vacua in IIB Calabi-Yau compactifications for multiparameter manifolds with an appropriate $\mathbb{Z}_{2}$ symmetry.
Philip Candelas, Xenia de la Ossa, Pyry Kuusela, Joseph McGovern
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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