Results 71 to 80 of about 10,606 (255)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Congruences between modular forms

open access: yes, 2023
We survey the connections between modular forms and representations of Galois groups that are predicted by the Langlands programme. We focus in particular on the applications of congruences between modular forms (through automorphy lifting theorems) to ...

core   +1 more source

Regularized inner products and meromorphic modular forms

open access: yes, 2017
In this talk, we consider a regularization of Petersson's inner product which is well-defined (and finite) between two meromorphic modular forms and agrees with Petersson's inner product whenever the latter exists.
Kane, BR
core   +1 more source

Flux vacua and modularity for $\mathbb{Z}_2$ symmetric Calabi-Yau manifolds

open access: yesSciPost Physics, 2023
We find continuous families of supersymmetric flux vacua in IIB Calabi-Yau compactifications for multiparameter manifolds with an appropriate $\mathbb{Z}_{2}$ symmetry.
Philip Candelas, Xenia de la Ossa, Pyry Kuusela, Joseph McGovern
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

On the arithmetic nature of coefficients of multiplicative eta-functions

open access: yesВестник Самарского университета: Естественнонаучная серия
In the article we study the arithmetic nature of the coefficients of multiplicative eta-products, also called McKay functions. For some functions it is possible to establish Hecke correspondence between the coefficients of McKay and Hecke grossen ...
G. V. Voskresenskaya
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Wach modules and Iwasawa theory for modular forms [PDF]

open access: yes
We define a family of Coleman maps for positive crystalline p-adic representations of the absolute Galois group of Qp using the theory of Wach modules.
Lei, Antonio   +2 more
core   +1 more source

Finite Modular Forms

open access: yesFinite Fields and Their Applications, 2001
The author develops a theory of modular forms for the fractional linear action of \(\Gamma:= \text{GL}(2,K)\) on the ``upper half plane'' \(\Omega:={\mathbf P}^1_K - {\mathbf P}^1(K)\), where \(K\) is a finite field. The theory looks like a shadow of the theory of classical or Drinfeld modular forms and, indeed, occurs naturally as the reduction of the
openaire   +2 more sources

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