Results 61 to 70 of about 2,907,134 (258)

Modular A 5 symmetry for flavour model building

Journal of High Energy Physics, 2019
In the framework of the modular symmetry approach to lepton flavour, we consider a class of theories where matter superfields transform in representations of the finite modular group Γ5 ≃ A 5.
P. P. Novichkov, J. T. Penedo, S. T. Petcov, A. V. Titov   +3 more
doaj   +1 more source

A CLASS OF NONHOLOMORPHIC MODULAR FORMS II: EQUIVARIANT ITERATED EISENSTEIN INTEGRALS

Forum of Mathematics, Sigma, 2020
We introduce a new family of real-analytic modular forms on the upper-half plane. They are arguably the simplest class of ‘mixed’ versions of modular forms of level one and are constructed out of real and imaginary parts of iterated integrals of ...
FRANCIS BROWN
doaj   +1 more source

Wach modules and Iwasawa theory for modular forms [PDF]

We define a family of Coleman maps for positive crystalline p-adic representations of the absolute Galois group of Qp using the theory of Wach modules.
Lei, Antonio, Loeffler, David, Zerbes, Sarah Livia   +2 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

On some automorphic properties of Galois traces of class invariants from generalized Weber functions of level 5

Open Mathematics, 2019
After the significant work of Zagier on the traces of singular moduli, Jeon, Kang and Kim showed that the Galois traces of real-valued class invariants given in terms of the singular values of the classical Weber functions can be identified with the ...
Eum Ick Sun, Jung Ho Yun
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Sp(6, Z) modular symmetry in flavor structures: quark flavor models and Siegel modular forms for $$\widetilde{\Delta }\left(96\right)$$

Journal of High Energy Physics
We study an approach to construct Siegel modular forms from Sp(6, Z). Zero-mode wave functions on T 6 with magnetic flux background behave Siegel modular forms at the origin.
Shota Kikuchi, Tatsuo Kobayashi, Kaito Nasu, Shohei Takada, Hikaru Uchida   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source