Results 111 to 120 of about 11,403,908 (364)
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Modular Functional Descriptions
Electronic Notes in Theoretical Computer Science, 2008 AbstractThe construction of reactive systems often requires the combination of different individual functionalities, thus leading to a complex overall behavior. To achieve an efficient construction of reliable systems, a structured approach to the definition of the behavior is needed. Here, functional modularization supports a separation of the overall
openaire +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Nonlinear Fredholm equations in modular function spaces
Electronic Journal of Differential Equations, 2019 We investigate the existence of solutions in modular function spaces of the Fredholm integral equation $$ \Phi(\theta) = g(\theta) + \int^1_0 f(\theta,\sigma, \Phi(\sigma)) \,d\sigma, $$ where $\Phi(\theta), g(\theta)\in L_{\rho}, \theta\in [0,1 ...
Mostafa Bachar
doaj
On modular functions in characteristic 𝑝 [PDF]
Transactions of the American Mathematical Society, 1978 Let k = F q ( T ) k\, = \,{{\textbf {F}}_q}\left ( T \right ) be a function field of one variable over a finite field
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Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Fixed point theorem and its application to perturbed integral equations in modular function spaces
Electronic Journal of Differential Equations, 2005 In this paper, we present a modular version of Krasnoselskii's fixed point theorem. Then this result is applied to the existence of solutions to perturbed integral equations in modular function spaces.
Ahmed Hajji, Elaidi Hanebaly
doaj
Systematic Discovery of Human Gene Function and Principles of Modular Organization through Phylogenetic Profiling [PDF]
, 2015 G.K. Dey +4 more
openalex +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source