Results 41 to 50 of about 3,074,877 (302)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Uniformization, accessory parameters and modular forms [PDF]

open access: yes, 2020
Several topics related to modular forms and to the accessory parameter problem for the uniformization of hyperbolic Riemann surfaces are discussed. In the first part of the thesis we present an algorithm for the computation of the accessory parameters ...
Bogo, G., Bogo, Gabriele
core  

Modularity of supersymmetric partition functions

open access: yesJournal of High Energy Physics, 2021
We discover a modular property of supersymmetric partition functions of supersymmetric theories with R-symmetry in four dimensions. This modular property is, in a sense, the generalization of the modular invariance of the supersymmetric partition ...
Abhijit Gadde
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Reconfigurable Innervation of Modular Soft Machines via Soft, Sticky, and Instant Electronic Adhesive Interlocking

open access: yesAdvanced Intelligent Systems, 2023
Adaptive and extreme changes in shape and configuration are the functional and morphological uniqueness of soft robots, but existing design approaches still rely on the predefined coordination of their “muscle” and “nerve” functions to produce such ...
Jaeyoung Yoon   +7 more
doaj   +1 more source

On Certain Generalizations of Rational and Irrational Equivariant Functions

open access: yesMathematics, 2022
In this paper, we address the case of a particular class of function referred to as the rational equivariant functions. We investigate which elliptic zeta functions arising from integrals of power of ℘, where ℘ is the Weierstrass ℘-function attached to a
Isra Al-Shbeil   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

On some new mixed modular equations involving Ramanujan's theta-functions [PDF]

open access: yes, 2014
In his second notebook, Ramanujan recorded altogether 23 P–Q modular equations involving his theta functions. In this paper, we establish several new mixed modular equations involving Ramanujan’s theta-functions ϕ and ψ which are akin to those recorded ...
Chandankumar, S.   +2 more
core  

The Hierarchical Modular Structure of HER2+ Breast Cancer Network

open access: yesFrontiers in Physiology, 2018
HER2-enriched breast cancer is a complex disease characterized by the overexpression of the ERBB2 amplicon. While the effects of this genomic aberration on the pathology have been studied, genome-wide deregulation patterns in this subtype of cancer are ...
Sergio Antonio Alcalá-Corona   +6 more
doaj   +1 more source

Quantum Modular Multiplication

open access: yesIEEE Access, 2020
Quantum modular multiplication circuit is one of the basic quantum computation circuits which are basic functions in quantum algorithms. However, since quantum-quantum modular multipliers require a high cost reversible modular inversion routine for ...
Seong-Min Cho   +4 more
doaj   +1 more source

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