Results 41 to 50 of about 3,074,877 (302)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Uniformization, accessory parameters and modular forms [PDF]
Several topics related to modular forms and to the accessory parameter problem for the uniformization of hyperbolic Riemann surfaces are discussed. In the first part of the thesis we present an algorithm for the computation of the accessory parameters ...
Bogo, G., Bogo, Gabriele
core
Modularity of supersymmetric partition functions
We discover a modular property of supersymmetric partition functions of supersymmetric theories with R-symmetry in four dimensions. This modular property is, in a sense, the generalization of the modular invariance of the supersymmetric partition ...
Abhijit Gadde
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Adaptive and extreme changes in shape and configuration are the functional and morphological uniqueness of soft robots, but existing design approaches still rely on the predefined coordination of their “muscle” and “nerve” functions to produce such ...
Jaeyoung Yoon +7 more
doaj +1 more source
On Certain Generalizations of Rational and Irrational Equivariant Functions
In this paper, we address the case of a particular class of function referred to as the rational equivariant functions. We investigate which elliptic zeta functions arising from integrals of power of ℘, where ℘ is the Weierstrass ℘-function attached to a
Isra Al-Shbeil +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
On some new mixed modular equations involving Ramanujan's theta-functions [PDF]
In his second notebook, Ramanujan recorded altogether 23 P–Q modular equations involving his theta functions. In this paper, we establish several new mixed modular equations involving Ramanujan’s theta-functions ϕ and ψ which are akin to those recorded ...
Chandankumar, S. +2 more
core
The Hierarchical Modular Structure of HER2+ Breast Cancer Network
HER2-enriched breast cancer is a complex disease characterized by the overexpression of the ERBB2 amplicon. While the effects of this genomic aberration on the pathology have been studied, genome-wide deregulation patterns in this subtype of cancer are ...
Sergio Antonio Alcalá-Corona +6 more
doaj +1 more source
Quantum Modular Multiplication
Quantum modular multiplication circuit is one of the basic quantum computation circuits which are basic functions in quantum algorithms. However, since quantum-quantum modular multipliers require a high cost reversible modular inversion routine for ...
Seong-Min Cho +4 more
doaj +1 more source

