Results 51 to 60 of about 481,122 (286)
DynaMod: dynamic functional modularity analysis [PDF]
A comprehensive analysis of enriched functional categories in differentially expressed genes is important to extract the underlying biological processes of genome-wide expression profiles. Moreover, identification of the network of significant functional modules in these dynamic processes is an interesting challenge.
Sun, CH Sun, Choong-Hyun +3 more
openaire +3 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
All-order differential equations for one-loop closed-string integrals and modular graph forms
We investigate generating functions for the integrals over world-sheet tori appearing in closed-string one-loop amplitudes of bosonic, heterotic and type-II theories.
Jan E. Gerken +2 more
doaj +1 more source
To the cusp and back: resurgent analysis for modular graph functions
Modular graph functions arise in the calculation of the low-energy expansion of closed-string scattering amplitudes. For toroidal world-sheets, they are SL(2, ℤ)-invariant functions of the torus complex structure that have to be integrated over the ...
Daniele Dorigoni +2 more
doaj +1 more source
Modular equations and distortion functions [PDF]
Modular equations occur in number theory, but it is less known that such equations also occur in the study of deformation properties of quasiconformal mappings. The authors study two important plane quasiconformal distortion functions, obtaining monotonicity and convexity properties, and finding sharp bounds for them.
Anderson, G. D. +2 more
openaire +3 more sources
Singular values of some modular functions
We study the properties of special values of the modular functions obtained from Weierstrass P-function at imaginary quadratic points.Comment: 19 pages,corrected ...
A. Enge +13 more
core +3 more sources
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
We define two-parameter generalizations of Andrews' $(k+1)$-marked odd Durfee symbols and $2k$th symmetrized odd rank moments, and study the automorphic properties of some of their generating functions.
Andrews +8 more
core +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source

