Results 51 to 60 of about 99,696 (310)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Hierarchical Modular Structure of HER2+ Breast Cancer Network
Frontiers in Physiology, 2018 HER2-enriched breast cancer is a complex disease characterized by the overexpression of the ERBB2 amplicon. While the effects of this genomic aberration on the pathology have been studied, genome-wide deregulation patterns in this subtype of cancer are ...
Sergio Antonio Alcalá-Corona +6 more
doaj +1 more source
Modularity of supersymmetric partition functions
Journal of High Energy Physics, 2021 We discover a modular property of supersymmetric partition functions of supersymmetric theories with R-symmetry in four dimensions. This modular property is, in a sense, the generalization of the modular invariance of the supersymmetric partition ...
Abhijit Gadde
doaj +1 more source
On Certain Generalizations of Rational and Irrational Equivariant Functions
Mathematics, 2022 In this paper, we address the case of a particular class of function referred to as the rational equivariant functions. We investigate which elliptic zeta functions arising from integrals of power of ℘, where ℘ is the Weierstrass ℘-function attached to a
Isra Al-Shbeil +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
All-order differential equations for one-loop closed-string integrals and modular graph forms
Journal of High Energy Physics, 2020 We investigate generating functions for the integrals over world-sheet tori appearing in closed-string one-loop amplitudes of bosonic, heterotic and type-II theories.
Jan E. Gerken +2 more
doaj +1 more source
Modular transformations of admissible N = 2 and Affine sl(2|1;C) characters [PDF]
, 2002 This thesis is a study of the affine super-algebra sl(2|l; C) and N = 2 superconformal algebra at fractional levels. In the first chapter we review background material on Conformal Field Theory, and how it appears in the context of string theory and the ...
Sadeghi, Jafar
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
To the cusp and back: resurgent analysis for modular graph functions
Journal of High Energy Physics, 2022 Modular graph functions arise in the calculation of the low-energy expansion of closed-string scattering amplitudes. For toroidal world-sheets, they are SL(2, ℤ)-invariant functions of the torus complex structure that have to be integrated over the ...
Daniele Dorigoni +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source