Results 71 to 80 of about 480,606 (330)

Arithmetic Hilbert Modular Functions II

Revista Matemática Iberoamericana, 1985
This work is a continuation of the author's earlier papers on Hilbert modular functions and arithmetic Hilbert modular forms. Here a q- expansion principle is established necessary to obtain reciprocity laws for special values of arithmetic Hilbert modular functions (associated to a totally real algebraic number field k) which subsumes the classical ...
openaire   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Modular Hamiltonians of excited states, OPE blocks and emergent bulk fields

Journal of High Energy Physics, 2018
We study the entanglement entropy and the modular Hamiltonian of slightly excited states reduced to a ball shaped region in generic conformal field theories.
Gábor Sárosi, Tomonori Ugajin
doaj   +1 more source

Three-loop contributions to the ρ parameter and iterated integrals of modular forms

Journal of High Energy Physics, 2020
We compute fully analytic results for the three-loop diagrams involving two different massive quark flavours contributing to the ρ parameter in the Standard Model.
Samuel Abreu, Matteo Becchetti, Claude Duhr, Robin Marzucca   +3 more
doaj   +1 more source

Constraints on Flavored 2d CFT Partition Functions

, 2018
We study the implications of modular invariance on 2d CFT partition functions with abelian or non-abelian currents when chemical potentials for the charges are turned on, i.e. when the partition functions are "flavored".
Dyer, Ethan, Fitzpatrick, A. Liam, Xin, Yuan   +2 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Modular anomaly of BPS black holes

Journal of High Energy Physics
Generating functions of BPS indices, counting states of D4-D2-D0 black holes in Calabi-Yau compactifications of type IIA string theory and identified with rank 0 Donaldson-Thomas invariants, are examples of mock modular forms.
Sergei Alexandrov, Khalil Bendriss
doaj   +1 more source

On Elliptic and Hyperbolic Modular Functions and the Corresponding Gudermann Peeta Functions

Axioms, 2015
In this article, we move back almost 200 years to Christoph Gudermann, the great expert on elliptic functions, who successfully put the twelve Jacobi functions in a didactic setting. We prove the second hyperbolic series expansions for elliptic functions
Thomas Ernst
doaj   +1 more source