Results 41 to 50 of about 58,936 (221)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Dynamics of compact quantum metric spaces

open access: yes, 2020
We provide a detailed study of actions of the integers on compact quantum metric spaces, which includes general criteria ensuring that the associated crossed product algebra is again a compact quantum metric space in a natural way.
Aguilar   +21 more
core   +1 more source

Best Proximity Point Results in Non-Archimedean Modular Metric Space [PDF]

open access: yesMathematics, 2017
In this paper, we introduce the new notion of Suzuki-type ( α , β , θ , γ ) -contractive mapping and investigate the existence and uniqueness of the best proximity point for such mappings in non-Archimedean modular metric space using the weak P λ -property.
Mohadeshe Paknazar, Manuel Sen
openaire   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Modular curves, C* algebras, and chaotic cosmology [PDF]

open access: yes, 2003
We make some brief remarks on the relation of the mixmaster universe model of chaotic cosmology to the geometry of modular curves and to noncommutative geometry.
Marcolli, Matilde
core   +1 more source

Modularity, Quaternion-Kahler spaces and Mirror Symmetry

open access: yes, 2013
We provide an explicit twistorial construction of quaternion-Kahler manifolds obtained by deformation of c-map spaces and carrying an isometric action of the modular group SL(2,Z).
Alexandrov, Sergei, Banerjee, Sibasish
core   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Non-Unique Fixed Point Theorems in Modular Metric Spaces [PDF]

open access: yesSymmetry, 2019
This paper is devoted to the study of Ćirić-type non-unique fixed point results in modular metric spaces. We obtain various theorems about a fixed point and periodic points for a self-map on modular spaces which are not necessarily continuous and satisfy certain contractive conditions.
openaire   +1 more source

Fixed point results for generalized F-contractions in modular metric and fuzzy metric spaces [PDF]

open access: yesFixed Point Theory and Applications, 2015
AbstractThe notion of modular metric space, being a natural generalization of classical modulars over linear spaces, was recently introduced. In this paper, we introduce a generalized F-contraction in modular metric space and investigate the existence of fixed points for such contractions.
Nawab Hussain, Abdul Latif, Iram Iqbal
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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