Results 51 to 60 of about 39,336 (226)
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Central characters for smooth irreducible modular representations of\n GL_2(Q_p) [PDF]
, 2011 Laurent Berger
openalex +2 more sources
Notes on the Verlinde formula in non-rational conformal field theories
, 2006 We review and extend evidence for the validity of a generalized Verlinde formula in particular non-rational conformal field theories. We identify a subset of representations of the chiral algebra in non-rational conformal field theories that give rise to
Charles Jego +5 more
core +2 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Modular generalized Springer correspondence: an overview [PDF]
, 2016 This is an overview of our series of papers on the modular generalized Springer correspondence. It is an expansion of a lecture given by the second author in the Fifth Conference of the Tsinghua Sanya International Mathematics Forum, Sanya, December 2014,
Achar, Pramod N. +3 more
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Ordinary pseudorepresentations and modular forms
, 2017 In this short note, we observe that the techniques of our recent work "Pseudo-modularity and Iwasawa theory" can be used to provide a new proof of some of the residually reducible modularity lifting results of Skinner and Wiles.
Wake, Preston, Wang-Erickson, Carl
core +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source