Results 41 to 50 of about 39,336 (226)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Strong modularity of reducible Galois representations [PDF]
, 2016 In this paper, we call strongly modular those reducible semi-simple odd mod $l$ Galois representations for which the conclusion of the strongest form of Serre's original modularity conjecture holds.
Billerey, Nicolas, Menares, Ricardo
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Conformal Boundary Conditions and what they teach us [PDF]
, 2001 The question of boundary conditions in conformal field theories is discussed, in the light of recent progress. Two kinds of boundary conditions are examined, along open boundaries of the system, or along closed curves or ``seams''.
Petkova, V. B., Zuber, J. -B.
core +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Un cas simple de correspondance de Jacquet-Langlands modulo l
, 2010 Let G be a general linear group over a p-adic field and let D^* be an anisotropic inner form of G. The Jacquet-Langlands correspondence between irreducible complex representations of D^* and discrete series of G does not behave well with respect to ...
Dat, Jean-Francois +1 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Categorification via blocks of modular representations II
, 2020 Bernstein, Frenkel and Khovanov have constructed a categorification of tensor products of the standard representation of $\mathfrak{sl}_2$ using singular blocks of category $\mathcal{O}$ for $\mathfrak{sl}_n$.
Nandakumar, Vinoth, Zhao, Gufang
core