Results 31 to 40 of about 39,336 (226)

Universal sectors of two-dimensional Carrollian CFTs

Journal of High Energy Physics
We revisit modular invariance in two-dimensional Carrollian conformal field theories from a geometric perspective. Focusing on the characters of the induced and highest-weight representations of the theory, we show that there are regions of parameter ...
Ankit Aggarwal, Arjun Bagchi, Stephane Detournay, Daniel Grumiller, Max Riegler, Joan Simón   +5 more
doaj   +1 more source

Singular Calabi-Yau Manifolds and ADE Classification of CFTs [PDF]

, 2000
We study superstring propagations on the Calabi-Yau manifold which develops an isolated ADE singularity. This theory has been conjectured to have a holographic dual description in terms of N=2 Landau-Ginzburg theory and Liouville theory.
Naka, Michihiro, Nozaki, Masatoshi
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Fusion Algebras and Characters of Rational Conformal Field Theories [PDF]

, 1995
We introduce the notion of (nondegenerate) strongly-modular fusion algebras. Here strongly-modular means that the fusion algebra is induced via Verlinde's formula by a representation of the modular group whose kernel contains a congruence subgroup ...
Eholzer, Wolfgang
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Kazhdan--Lusztig-dual quantum group for logarithmic extensions of Virasoro minimal models

, 2007
We derive and study a quantum group g(p,q) that is Kazhdan--Lusztig-dual to the W-algebra W(p,q) of the logarithmic (p,q) conformal field theory model. The algebra W(p,q) is generated by two currents $W^+(z)$ and $W^-(z)$ of dimension (2p-1)(2q-1), and ...
A. M. Gainutdinov, A. M. Semikhatov, B. L. Feigin, Chari V., Drinfeld V. G., I. Yu. Tipunin, Kerler T., Sweedler M. E.   +7 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Level-rank duality of the U(N) WZW model, Chern-Simons theory, and 2d qYM theory [PDF]

, 2007
We study the WZW, Chern-Simons, and 2d qYM theories with gauge group U(N). The U(N) WZW model is only well-defined for odd level K, and this model is shown to exhibit level-rank duality in a much simpler form than that for SU(N).
A. Kuniba, C. Beasley, C. Vafa, D. Gepner, D. Jafferis, E. Witten, Howard J Schnitzer, I. Frenkel, J.M.F. Labastida, M. Aganagic, M. Aganagic, M. Blau, M. Blau, M. Marino, M.R. Douglas, N. Caporaso ., N. Caporaso ., N. Caporaso ., R. Gopakumar, S. de Haro, S. de Haro, Stephen G Naculich   +21 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source