Results 61 to 70 of about 471,136 (289)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Modular flow of excited states
Journal of High Energy Physics, 2021 We develop new techniques for studying the modular and the relative modular flows of general excited states. We show that the class of states obtained by acting on the vacuum (or any cyclic and separating state) with invertible operators from the algebra
Nima Lashkari +2 more
doaj +1 more source
Emergence of kinematic space from quantum modular geometric tensor
Physics Letters B, 2022 We generalize the Quantum Geometric Tensor by replacing a Hamiltonian with a modular Hamiltonian. The symmetric part of the Quantum Geometric Tensor provides a Fubini-Study metric, and its anti-symmetric sector gives a Berry curvature. Our generalization
Xing Huang, Chen-Te Ma
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
, 2019 We construct a family of Poisson structures of hydrodynamic type on the loop space of $\mathbb{C} P^{n-1}$. This family is parametrized by the moduli space of elliptic curves or, in other words, by the modular parameter $\tau$.
Odesskii, Alexander
core +1 more source
Applied Mathematics, 2013 In this paper, we present and discuss the topology of modular spaces using the filter base and we then characterize closed subsets as well as its regularity.
openaire +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Generalized modular fractal spaces and fixed point theorems
Advances in Difference Equations, 2021 In this article, we introduce a new concept of Hausdorff distance through generalized modular metric on nonempty compact subsets and study some topological properties of it.
Alireza Alihajimohammad, Reza Saadati
doaj +1 more source
Linear manifolds in the moduli space of one-forms
, 2007 We study closures of GL_2(R)-orbits on the total space of the Hodge bundle over the moduli space of curves under the assumption that they are algebraic manifolds.
Moeller, Martin
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source