Results 41 to 50 of about 80,665 (262)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Basic Body Plans for Soft Modular Pneubotics in Architecture

Prostor, 2019
This article introduces a theoretical model for the design of pneubotic structures that can be constructed and actuated by using the modular unit volume element.
Davor Andrić, Karin Šerman, Josip Galić   +2 more
doaj   +1 more source

Integration of origami and deployable concept in volumetric modular units

Scientific Reports, 2022
Modular building systems (MBS) and Origami are two emerging methods used in current construction practice. Origami is directly associated with the principles of the ancient Japanese art of paper folding, characterised by high morphological possibilities ...
Valentina Beatini, Perampalam Gatheeshgar, Heshachanaa Rajanayagam, Keerthan Poologanathan, Thadshajini Suntharalingam, Dilini Perera, Elilarasi Kanthasamy, Brabha Nagaratnam   +7 more
doaj   +1 more source

Decomposition and Modular Structure of BioPortal Ontologies [PDF]

, 2011
We present the first large scale investigation into the modular structure of a substantial collection of state-of-the-art biomedical ontologies, namely those maintained in the NCBO BioPortal repository. Using the notion of Atomic Decomposition, we partition BioPortal ontologies into logically coherent subsets (atoms), which are related to each other by
Chiara Del Vescovo, Damian Gessler, Pavel Klinov, Bijan Parsia, Ulrike Sattler, Thomas Schneider 0002, Andrew Winget   +6 more
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Cubiertas para viñedos

ARQ, 2003
Una realidad de recursos y tecnologías limitadas, situada en un ambiente climático amable, es el lugar de exploración de este taller conjunto entre las escuelas de arquitectura de la Pontificia Universidad Católica de Chile y de la Universidad Ricardo ...
Teodoro Fernández, Pilar García, Paulina Courard   +2 more
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Modular and Self-Scalable Origami Robot: A First Approach

Mathematics, 2021
This paper presents a proposal of a modular robot with origami structure. The proposal is based on a self-scalable and modular link made of soft parts. The kinematics of a single link and several links interconnected is studied and validated.
Lisbeth Mena, Jorge Muñoz, Concepción A. Monje, Carlos Balaguer   +3 more
doaj   +1 more source

Learning of modular structured networks

Artificial Intelligence, 1995
AbstractLearning of large-scale neural networks suffers from computational cost and the local minima problem. One solution to these difficulties is the use of modular structured networks. Proposed here is the learning of modular networks using structural learning with forgetting. It enables the formation of modules.
openaire   +1 more source

The modular structure of informational sequences

Biosystems, 1996
It is shown that DNA sequences can be decomposed into smaller units much the same as texts can be decomposed into syllables, words, or groups of words. Those smaller units (modules) are extracted from DNA sequences according to statistical criteria. Tests with sequences of known modular structure (two novels and a FORTRAN source code) were performed ...
Schmitt, Armin O., Ebeling, Werner, Herzel, Hanspeter   +2 more
openaire   +3 more sources