Results 41 to 50 of about 212,419 (273)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Frontiers in Ecology and Evolution, 2020 Developmental modularity has long been viewed as a hierarchical organization that facilitates evolution through modification or reuse of preexisting modules.
James J. Lewis, Steven M. Van Belleghem
doaj +1 more source
Configuration Optimization for Sustainable Temporary Houses Employing BIM Procedure
Buildings, 2023 Building information modeling (BIM) is a process for managing the construction information model. The possibility of managing very complex construction orders using information processes has made the work of designers both easier and more productive.
Viviana Tirella +4 more
doaj +1 more source
Ground state energy of $q$-state Potts model: the minimum modularity
, 2014 A wide range of interacting systems can be described by complex networks. A common feature of such networks is that they consist of several communities or modules, the degree of which may quantified as the \emph{modularity}.
B. Kahng +7 more
core +1 more source
Bad Communities with High Modularity [PDF]
, 2013 In this paper we discuss some problematic aspects of Newman's modularity function QN. Given a graph G, the modularity of G can be written as QN = Qf -Q0, where Qf is the intracluster edge fraction of G and Q0 is the expected intracluster edge fraction of
Kehagias, Athanasios +1 more
core +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
An a posteriori measure of network modularity [v3; ref status: indexed, http://f1000r.es/2ju]
F1000Research, 2013 Measuring the modularity of networks, and how it deviates from random expectations, important to understand their structure and emerging properties. Several measures exist to assess modularity, which when applied to the same network, can return both ...
Timothée Poisot
doaj +1 more source
Life, 2022 Introduction: For many years, anatomical studies have been conducted with a shattered view of the body. Although the study of the different apparatuses provides a systemic view of the human body, the reconstruction of the complex network of anatomical ...
Daniele Della Posta +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Climate change in reclamation landscapes – Adaptation between module and modularity
Agathón, 2023 Modern drainage of wetlands has produced landscapes that are expressions of a productive view of natural space. These landscapes result from a profound environmental transformation driven by economic, social, health, and cultural reasons.
Carla Brisotto +3 more
doaj +1 more source