Results 71 to 80 of about 59,609 (323)
BMC Evolutionary Biology, 2019 Background Understanding how variation in gene expression contributes to morphological diversity is a major goal in evolutionary biology. Cichlid fishes from the East African Great lakes exhibit striking diversity in trophic adaptations predicated on the
Ehsan Pashay Ahi +4 more
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Stability and Robustness of Unbalanced Genetic Toggle Switches in the Presence of Scarce Resources
Life, 2021 While the vision of synthetic biology is to create complex genetic systems in a rational fashion, system-level behaviors are often perplexing due to the context-dependent dynamics of modules.
Chentao Yong, Andras Gyorgy
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FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
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A Model of Genome Size Evolution for Prokaryotes in Stable and Fluctuating Environments [PDF]
, 2015 Temporal variability in ecosystems significantly impacts species diversity and ecosystem productivity and therefore the evolution of organisms. Different levels of environmental perturbations such as seasonal fluctuations, natural disasters, and global ...
Adami +9 more
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Phylogenetic analysis of modularity in protein interaction networks
BMC Bioinformatics, 2009 Background In systems biology, comparative analyses of molecular interactions across diverse species indicate that conservation and divergence of networks can be used to understand functional evolution from a systems perspective.
Bebek Gurkan +4 more
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Combinatorial drug screening on 3D Ewing sarcoma spheroids using droplet-based microfluidics
iScience, 2023 Summary: Culturing and screening cells in microfluidics, particularly in three-dimensional formats, has the potential to impact diverse areas from fundamental biology to cancer precision medicine.
Romain Fevre +6 more
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Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Frontiers in Plant Science, 2020 Understanding why some plant lineages move from one climatic region to another is a mayor goal of evolutionary biology. In the southern Andes plant lineages that have migrated along mountain ranges tracking cold-humid climates coexist with lineages that ...
Fernanda Pérez +10 more
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FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
The Drink You Have When You’re Not Having a Drink [PDF]
, 2008 The Architecture of the Mind is itself built on foundations that deserve probing. In this brief commentary I focus on these foundations—Carruthers’ conception of modularity, his arguments for thinking that the mind is massively modular in structure ...
Wilson, Robert A.
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