Results 1 to 10 of about 2,950,352 (332)

Peptide Super-Agonist Enhances T-Cell Responses to Melanoma

Frontiers in Immunology, 2019
Recent immunotherapeutic approaches using adoptive cell therapy, or checkpoint blockade, have demonstrated the powerful anti-cancer potential of CD8 cytotoxic T-lymphocytes (CTL).
Sarah A. E. Galloway, Garry Dolton, Meriem Attaf, Aaron Wall, Anna Fuller, Cristina Rius, Valentina Bianchi, Sarah Theaker, Angharad Lloyd, Angharad Lloyd, Marine E. Caillaud, Inge Marie Svane, Marco Donia, David K. Cole, David K. Cole, Barbara Szomolay, Pierre Rizkallah, Andrew K. Sewell, Andrew K. Sewell   +18 more
doaj   +1 more source

Recombination Parameters of the Diffusion Region and Depletion Region for Crystalline Silicon Solar Cells under Different Injection Levels

Applied Sciences, 2020
In order to maximize performance in all conditions of use, and to model exactly the performance of solar cells, it is very important to study the recombination parameters under different injection levels.
Qiaoqiao Bai, Hong Yang, Xiaoli Cheng, He Wang   +3 more
doaj   +1 more source

Organelle Interaction and Drug Discovery: Towards Correlative Nanoscopy and Molecular Dynamics Simulation

Frontiers in Pharmacology, 2022
The inter-organelle interactions, including the cytomembrane, endoplasmic reticulum, mitochondrion, lysosome, dictyosome, and nucleus, play the important roles in maintaining the normal function and homeostasis of cells. Organelle dysfunction can lead to
Zhiwei Yang, Zhiwei Yang, Zichen Zhang, Yizhen Zhao, Qiushi Ye, Xuhua Li, Lingjie Meng, Lingjie Meng, Jiangang Long, Shengli Zhang, Lei Zhang   +10 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Soluble CD83 Triggers Resolution of Arthritis and Sustained Inflammation Control in IDO Dependent Manner

Frontiers in Immunology, 2019
Interference with autoimmune-mediated cytokine production is a key yet poorly developed approach to treat autoimmune and inflammatory diseases such as rheumatoid arthritis.
Dmytro Royzman, Darja Andreev, Lena Stich, Manfred Rauh, Tobias Bäuerle, Stephan Ellmann, Louis Boon, Markus Kindermann, Katrin Peckert, Aline Bozec, Georg Schett, Alexander Steinkasserer, Elisabeth Zinser   +12 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A FtsZ cis disassembly element acts in Z-ring assembly during bacterial cell division

Nature Communications
Bacterial cell division hinges on the Z-ring, an architecture built from the dynamical assembly and disassembly of FtsZ proteins. This delicate balance ensures not only apparent stability, but also continuous remodeling, both of which are required for Z ...
Huijia Yin, Yang Liu, Ying Zhao, Pengyue Chen, Zengyi Chang   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The Konkoly Blazhko Survey: Is light-curve modulation a common property of RRab stars?

, 2009
A systematic survey to establish the true incidence rate of the Blazhko modulation among short-period, fundamental-mode, Galactic field RR Lyrae stars has been accomplished. The Konkoly Blazhko Survey (KBS) was initiated in 2004. Since then more than 750
Alard, Alcock, B. Belucz, B. Szeidl, Bookmeyer, Castellani, Collinge, ESA, Fitch, G. Hajdu, I. Nagy, J. Jurcsik, Jones, Jurcsik, Jurcsik, Jurcsik, Jurcsik, Jurcsik, Jurcsik, Jurcsik, Jurcsik, Jurcsik, Jurcsik, Jurcsik, K. Posztob��nyi, K. Vida, Kholopov, Kolenberg, Kov��cs, Kov��cs, Kun, L. Moln��r, Layden, Lub, M. V��radi, Mizerski, Moskalik, Pojmanski, Preston, Schmidt, Shibahashi, Smith, Smith, Smolec, Soszy��ski, Sturch, Suntzeff, Szczygie��, Szeidl, Szeidl, S��dor, S��dor, S��dor, S��dor, Wils, Wo��niak, Zs. Hurta, Zs. K��v��ri, ��. S��dor   +58 more
core   +1 more source

Stabilities, Electronic Structures, and Bonding Properties of Iron Complexes (E1E2)Fe(CO)2(CNArTripp2)2 (E1E2=BF, CO, N2, CN−, or NO+)**

ChemistryOpen, 2020
The coordination of 10‐electron diatomic ligands (BF, CO N2) to iron complexes Fe(CO)2(CNArTripp2)2 [ArTripp2=2,6‐(2,4,6‐(iso‐propyl)3C6H2)2C6H3] have been realized in experiments very recently (Science, 2019, 363, 1203–1205).
Gerui Pei, Dr. Pei Zhao, Song Xu, Xintian Zhao, Prof. Chuncai Kong, Prof. Zhimao Yang, Prof. Masahiro Ehara, Prof. Tao Yang   +7 more
doaj   +1 more source