Results 81 to 90 of about 1,844,961 (296)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Optimum Mode-Switching-Assisted Constant-Power Single- and Multicarrier Adaptive Modulation
, 2003 A set of optimum mode-switching levels is derived for a generic constant-power adaptive-modulation scheme based on a closed-form expression of the average bit error ratio (BER) and the average bits-per-symbol (BPS) throughput of the adaptive-modulation ...
Choi, B.J., Hanzo, L.
core +1 more source
Frontiers in Immunology, 2019 Interference with autoimmune-mediated cytokine production is a key yet poorly developed approach to treat autoimmune and inflammatory diseases such as rheumatoid arthritis.
Dmytro Royzman +12 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2002 The performance of burst-by-burst adaptive modulation is studied in conjunction with reduced complexity turbo equalization over a wideband multi-path Rayleigh fading channel.
Wong, C H, Yeap, B L, Hanzo, L
core +1 more source
Diance yu yibiaoIn order to further improve the economic benefits of pumped storage power stations participating in the electricity market, an intra-day real-time optimal scheduling method for pumped storage power stations based on the evaluation of electricity energy ...
ZHAO Zengtao +4 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Superior Bs and bending ductility in Fe-Si-B-C-P-Cu nanocrystalline alloys with high Fe content
Review of Materials ResearchOwing to excellent soft magnetic properties, Fe based nanocrystalline amorphous materials with high Fe content exhibit significant potential for applications in next-generation power electronic devices.
Sidan Ding +11 more
doaj +1 more source