Results 71 to 80 of about 2,665,852 (303)

Interaction of non-targeted nanodiamond carriers with specialized rodent cells: preliminary ex vivo and in vivo study

open access: yesJournal of BioScience and Biotechnology, 2022
Nanodiamonds are widely tested as convenient drug delivery systems because they are nontoxic, biocompatible, and can easily carry various biomolecules. However, their effect on living systems is not fully explored.
Eva Neuhöferová   +3 more
doaj  

Daily modulation and gravitational focusing in direct dark matter search experiments [PDF]

open access: yes, 2015
We study the effect of gravitational focusing of the earth on dark matter. We find that the effect can produce a detectable diurnal modulation in the dark matter signal for part of the parameter space which for high dark matter masses is larger than the ...
Kouvaris, Chris   +1 more
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Peptide Super-Agonist Enhances T-Cell Responses to Melanoma

open access: yesFrontiers in Immunology, 2019
Recent immunotherapeutic approaches using adoptive cell therapy, or checkpoint blockade, have demonstrated the powerful anti-cancer potential of CD8 cytotoxic T-lymphocytes (CTL).
Sarah A. E. Galloway   +18 more
doaj   +1 more source

Recombination Parameters of the Diffusion Region and Depletion Region for Crystalline Silicon Solar Cells under Different Injection Levels

open access: yesApplied Sciences, 2020
In order to maximize performance in all conditions of use, and to model exactly the performance of solar cells, it is very important to study the recombination parameters under different injection levels.
Qiaoqiao Bai   +3 more
doaj   +1 more source

DUO MODULES [PDF]

open access: yesGlasgow Mathematical Journal, 2006
Let R be a ring. An R-module M is called a (weak) duo module provided every (direct summand) submodule of M is fully invariant. It is proved that if R is a commutative domain with field of fractions K then a torsion-free uniform R-module is a duo module if and only if every element k in K such that kM is contained in M belongs to R.
Ozcan, A.C., Harmanci, A., Smith, P.F.
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Soluble CD83 Triggers Resolution of Arthritis and Sustained Inflammation Control in IDO Dependent Manner

open access: yesFrontiers in Immunology, 2019
Interference with autoimmune-mediated cytokine production is a key yet poorly developed approach to treat autoimmune and inflammatory diseases such as rheumatoid arthritis.
Dmytro Royzman   +12 more
doaj   +1 more source

Organelle Interaction and Drug Discovery: Towards Correlative Nanoscopy and Molecular Dynamics Simulation

open access: yesFrontiers in Pharmacology, 2022
The inter-organelle interactions, including the cytomembrane, endoplasmic reticulum, mitochondrion, lysosome, dictyosome, and nucleus, play the important roles in maintaining the normal function and homeostasis of cells. Organelle dysfunction can lead to
Zhiwei Yang   +10 more
doaj   +1 more source

Fitting Blazhko light curves

open access: yes, 2012
The correct amplitude and phase modulation formalism of the Blazhko modulation is given. The harmonic order dependent amplitude and phase modulation form is equivalent with the Fourier decomposition of multiplets.
Alcock   +26 more
core   +1 more source

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