Results 91 to 100 of about 299,236 (294)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
In the open-winding motor fed by a common DC bus, unbalanced inverter common-mode voltage (CMV), zero-sequence components of the permanent magnet flux linkage, and the PWM dead-time effect can induce a zero-sequence current (ZSC) through the inherent ...
Weijie Hao, Yiguang Chen
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Modulation Index Estimation of Frequency and Phase Modulated Signals
Modulation index estimation is important in the demodulation and recognition of Angle Modulation (AM) signals which include Frequency Modulation (FM) and Phase Modulation (PM) signals. In this paper, we firstly analyzed the AM signals with baseband modulation types, such as monotone, PSK, FSK, in the time and frequency domain.
Geng Peng +3 more
openaire +2 more sources
Detecting structural defects is one of the primary challenges engineers face. Consequently, the development of techniques and methods capable of detecting structural defects has always been critical.
Mohammad M. Bazrafkan +2 more
doaj +1 more source
Modular multilevel converters (MMCs) operate in the low modulation index region in many applications. However, when utilized at the low modulation index region, large harmonics appear in the output voltage, which degrade the performance of the MMC.
Fayun ZHOU +6 more
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Detect-and-forward relaying aided cooperative spatial modulation for wireless networks
A novel detect-and-forward (DeF) relaying aided cooperative SM scheme is proposed, which is capable of striking a flexible tradeoff in terms of the achievable bit error ratio (BER), complexity and unequal error protection (UEP).
Yang, Ping +6 more
core +1 more source
This paper presents a proposal of an open-source index modulation (IM) toolkit, which facilitates reproducible research and accelerates open innovation in IM studies.
Naoki Ishikawa
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

