The cspA mRNA Is a Thermosensor that Modulates Translation of the Cold-Shock Protein CspA [PDF]
Anna Maria Giuliodori +7 more
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Editorial: New insights into caring for pediatric patients with cystic fibrosis
Stephanie Bui +9 more
doaj +1 more source
Nematode parasites have shown resistance to the anthelmintics, ivermectin and moxidectin, and there is evidence that the over-expression of parasite P-glycoprotein (P-gp) may account, at least in part, for resistance to ivermectin.
Molento Marcelo B., Prichard Roger K.
doaj
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Pharmacological rescue of the G85E CFTR variant by preclinical and approved modulators
IntroductionCystic Fibrosis (CF) is a genetic disease due to loss-of-function mutations of the CFTR channel. F508del is the most frequent mutation (70% of alleles in Italy), while other mutations have much lower frequency.
Valeria Tomati +23 more
doaj +1 more source
Oxidised LDL modulate adipogenesis in 3T3‐L1 preadipocytes by affecting the balance between cell proliferation and differentiation [PDF]
Roberta Masella +11 more
openalex +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca2+ release [PDF]
X. Tian +4 more
openalex +1 more source

