Results 111 to 120 of about 1,272,107 (311)

Simultaneous high stiffness and metal-like superelasticity in TiB2–Ni coatings revealed by in-situ TEM nanoindentation

open access: yesMaterials Research Express
Titanium diboride (TiB _2 ) coatings possess excellent functional and structural properties, including high hardness, good abrasion resistance, superior thermal conductivity and outstanding electrical properties.
Dongdong Liu   +7 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Parallel distributed implementation of workflow management module for operation support system for telecommunication providers

open access: yes, 2017
There is provided parallel distributed implementation of workflow management module for operation support system for telecommunication providers based on Hadoop framework.
Shykhutska, S.O., Doroshenko, А.Yu.
core  

The on-board maritime PNT Module – Concept and preliminary experimental results [PDF]

open access: yes, 2012
Improvement and Indication of Reliability have been identified as important user needs within the e-Navigation strategy of the International Maritime Organization (IMO).
Ziebold, Ralf   +3 more
core  

Producing websites for assessment: A case study from a Level 1 fieldwork module [PDF]

open access: yes, 2004
This is a PDF version of an article published in Journal of Geography in Higher Education© 2004. The definitive version is available at http://www.tandf.co.uk/journals/carfax/.
France, Derek, Ribchester, Chris
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Reengineering of Module for Public Sector [PDF]

open access: yes, 2011
This paper is based on reengineering of module for public sector, it deals with the measurement of complexity as well as effort measurement of module during Reengineering of module at design time.
Dr. Anil Kumar
core  

Home - About - Disclaimer - Privacy