Results 111 to 120 of about 1,229,228 (308)

Decompositions of modules into projective modules and CS-modules [PDF]

open access: yesBulletin of the Australian Mathematical Society, 2000
Let M be a right R-module. It is shown that M is a locally Noetherian module if every finitely generated module in σ[M] is a direct sum of a projective module and a CS-module. Moreover, if every module in σ[M] is a direct sum of a projective module and a CS-module, then every module in σ[M] is a direct sum of modules which are either indecomposable ...
openaire   +2 more sources

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Parallel distributed implementation of workflow management module for operation support system for telecommunication providers

open access: yes, 2017
There is provided parallel distributed implementation of workflow management module for operation support system for telecommunication providers based on Hadoop framework.
Shykhutska, S.O., Doroshenko, А.Yu.
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

supportDM module 1: introducing research data management

open access: yes, 2014
Introductory module on research data management, part of the supportDM course aimed at those in RDM support roles. Suitable for staff in library, IT and research office settings.
John Murtagh, Stephen Grace, Sarah Jones
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CESNET/perun-simplesamlphp-module v3.4

open access: yes, 2019
Module which allows simpleSAMLphp to get data from ...
BaranekD   +5 more
core   +1 more source

Acceptability and feasibility of a community–hospital parenting support and prevention programme for families of infants at high neurodevelopmental risk following neonatal encephalopathy: protocol of the PRePaR (PRevention and support for Parenthood in early Rehabilitation) mixed-methods study

open access: yesBMJ Open
Introduction Neonatal encephalopathy, particularly situations involving neonatal hypoxic–ischaemic encephalopathy (NHIE) and neonatal stroke (NS), covers complex neonatal conditions associated with a risk of neurodevelopmental difficulties.
Paul Ornetti   +6 more
doaj   +1 more source

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