Results 121 to 130 of about 1,229,228 (308)
Motivated by the example of finite fields and quasi-finite fields, \textit{D. Macpherson} and \textit{C. Steinhorn} [Trans. Am. Math. Soc. 360, No. 1, 411--448 (2008; Zbl 1127.03026)] introduced a dimension/measure theory for certain classes of finite structures. This concept was developed further in [\textit{R. Elwes} and \textit{D. Macpherson}, Lond.
openaire +2 more sources
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
supportDM module 3: data management planning
Third module data management planning, part of the supportDM course aimed at those in RDM support roles. Suitable for staff in library, IT and research office settings.
Sarah Jones
core
ds-modules/Module-Feedback v1.0
Analysis of feedback on module ...
Josh Quan
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Expression of the C-terminal family 22 carbohydrate-binding module of xylanase 10B of Clostridium themocellum in tobacco plant [PDF]
Carbohydrate-binding modules have been shown to alter plant cell wall structural architecture. Hence, they have the potential application of being used to engineer the plant to produce tailor-made natural fibers in the cell wall.
Olawole, O.
core
Observation of logic states of HfO2-based ferroelectric FETs using STEM-DPC [PDF]
Nemec Thorgund +6 more
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source

