Results 131 to 140 of about 1,272,107 (311)

Legal position of the European Central Bank in contemporary social discourse

open access: yesPravo
This paper analyzes the legal position of the European Central Bank (ECB) within the context of contemporary social conditions, focusing on the ECB’s tendency to expand its competencies and the judicial evaluation of the current monetary legislation in ...
Marko Dimitrijević
doaj   +1 more source

Modulating Modulation [PDF]

open access: yesThe Journal of General Physiology, 2000
openaire   +2 more sources

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Measurability in modules

open access: yesArchive for Mathematical Logic, 2014
Motivated by the example of finite fields and quasi-finite fields, \textit{D. Macpherson} and \textit{C. Steinhorn} [Trans. Am. Math. Soc. 360, No. 1, 411--448 (2008; Zbl 1127.03026)] introduced a dimension/measure theory for certain classes of finite structures. This concept was developed further in [\textit{R. Elwes} and \textit{D. Macpherson}, Lond.
openaire   +2 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Acute and chronic effects of local muscle vibration training inducing illusions on wrist strength and neurophysiological measures

open access: yesScientific Reports
Local muscle vibrations (LMV) acutely and chronically affect the sensorimotor system, but their effects vary depending on application conditions. The mechanisms behind repeated LMV exposure are still debated.
Sophie Julliand   +7 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

A Rapid and Inexpensive Method for Finding the Basic Parameters of Involute Helical Gears

open access: yesApplied Sciences
The paper proposes a rapid, straightforward, and inexpensive method for finding the basic parameters of helical gears with an involute profile. The basic parameters envisaged are the normal module, normal profile shift coefficient, and the helix angle ...
Stelian Alaci   +5 more
doaj   +1 more source

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