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Correlation profile of the external-module-set1 gene-modules in the matched datasets. [PDF]

open access: yes, 2018
Correlation of the full-module scores of the external-module-set1 gene-modules (manually extracted from literature) computed from ref-1/ref-2/ref-3 reference dataset to the respective full-module/module-subset scores computed from the matched datasets ...
Françoise Rothé (215567)   +6 more
core   +1 more source

Acceptability and feasibility of a community–hospital parenting support and prevention programme for families of infants at high neurodevelopmental risk following neonatal encephalopathy: protocol of the PRePaR (PRevention and support for Parenthood in early Rehabilitation) mixed-methods study

open access: yesBMJ Open
Introduction Neonatal encephalopathy, particularly situations involving neonatal hypoxic–ischaemic encephalopathy (NHIE) and neonatal stroke (NS), covers complex neonatal conditions associated with a risk of neurodevelopmental difficulties.
Paul Ornetti   +7 more
doaj   +1 more source

Measurability in modules

open access: yesArchive for Mathematical Logic, 2014
Motivated by the example of finite fields and quasi-finite fields, \textit{D. Macpherson} and \textit{C. Steinhorn} [Trans. Am. Math. Soc. 360, No. 1, 411--448 (2008; Zbl 1127.03026)] introduced a dimension/measure theory for certain classes of finite structures. This concept was developed further in [\textit{R. Elwes} and \textit{D. Macpherson}, Lond.
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

illustration of a lunar module [PDF]

open access: yes
An illustration of lunar, or planetary module, sitting on the surface of that ...

core  

supportDM module 2: Guidance and support for researchers [PDF]

open access: yes, 2014
Second module discussing what guidance and support to offer to researchers managing data, part of the supportDM course aimed at those in RDM support roles. Suitable for staff in library, IT and research office settings. The online module is in Xerte, and
John Murtagh, Stephen Grace, Sarah Jones
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Module and Interface from the Transaction Cost Approach [PDF]

open access: yes, 2005
Although module as a unit sharing multiple interfaces to interact, integrate and combine is a common definition, interface has been referred to in very few researches of modularity.
Ueda, Masashi, Suematsu, Chihiro
core  

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