Results 191 to 200 of about 68,443 (267)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A mechanical model based on watermelons for the study of dynamic cranial remolding orthoses. [PDF]

Sci Rep
Veloso F, Morais P, Torres H, Fritze A, Rüdiger M, Hahn G, Pinho ACM, Correia-Pinto J, Vilaça JL.   +8 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Indirect 3D printing in tissue engineering: expanding materials used for improved scaffold functionality. [PDF]

Biomed Eng Online
Bahraminasab M, Arabhalvaei M, Ghanbari MA.   +2 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Advances in the Diagnosis of Invasive Pulmonary Mold Infections: Focus on Diagnostic Performance and Cost-Effectiveness of Diagnostic Tests. [PDF]

Diagnostics (Basel)
Papadimatos S, Tziotis A, Arvanitis P, Le-Mahajan A, Farmakiotis D.   +4 more
europepmc   +1 more source

The Influence of Furfuryl Resin Type-Classical and Designed for Sand 3D Printing-On Cast Iron Casting Microstructure and Surface Roughness. [PDF]

Polymers (Basel)
Major-Gabryś K, Halejcio D, Fijołek A, Marosz J, Górny M.   +4 more
europepmc   +1 more source

Cutaneous Paraconiothyrium cyclothyrioides Infection in Lung Transplant Recipient, Georgia, USA. [PDF]

Emerg Infect Dis
Mackey C, Thomas S, Witt LS, Sajewski E, Lockhart SR, Pouch SM, Cheeley J, MacKelfresh JB, Gold JAW.   +8 more
europepmc   +1 more source

Integrated Experimental-Computational Framework for Drug Transport Quantification in 3D <i>Microtissues</i>™. [PDF]

Micromachines (Basel)
Fariha R, Hamze J, Okoh OD, Rothkopf E, Tripathi A.   +4 more
europepmc   +1 more source