Plasma oxidative stress in reproduction of two eusocial African mole-rat species, the naked mole-rat and the Damaraland mole-rat [PDF]
Frontiers in Zoology, 2021 One of the most prominent life-history trade-offs involves the cost of reproduction. Oxidative stress has been proposed to be involved in this trade-off and has been associated with reduced life span.
Paul Juan Jacobs +2 more
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Gene losses may contribute to subterranean adaptations in naked mole-rat and blind mole-rat [PDF]
BMC Biology, 2022 Background Naked mole-rats (Heterocephalus glaber, NMRs) and blind mole-rats (Spalax galili, BMRs) are representative subterranean rodents that have evolved many extraordinary traits, including hypoxia tolerance, longevity, and cancer resistance ...
Zhizhong Zheng +4 more
doaj +6 more sources
Alone, in the dark: The extraordinary neuroethology of the solitary blind mole rat
eLife, 2022 On the social scale, the blind mole rat (BMR; Spalax ehrenbergi) is an extreme. It is exceedingly solitary, territorial, and aggressive. BMRs reside underground, in self-excavated tunnels that they rarely leave.
Yael Kashash +4 more
doaj +2 more sources
Frontiers in Ecology and Evolution, 2022 The Naked mole-rat (NMR) is becoming a prominent model organism due to its peculiar traits, such as eusociality, extreme longevity, cancer resistance, and reduced pain sensitivity.
Guillermo Serrano Nájera, Koryu Kin
doaj +2 more sources
Invariant γδTCR natural killer-like effector T cells in the naked mole-rat [PDF]
Nature CommunicationsThe naked mole-rat (Heterocephalus glaber) is a long-lived rodent species showing resistance to the development of cancer. Although naked mole-rats have been reported to lack natural killer (NK) cells, γδ T cell-based immunity has been suggested in this ...
Guillem Sanchez Sanchez +7 more
doaj +2 more sources
Epigenetic aging of the demographically non-aging naked mole-rat [PDF]
Nature Communications, 2022 The exceptionally long-lived naked mole-rat is characterized by the lack of increased mortality with aging. Here the authors perform epigenetic studies to show that naked mole-rats epigenetically age despite their non-increasing mortality rate.
Csaba Kerepesi +15 more
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Non-Invasive Quantification of Faecal and Urine Reproductive Hormone Metabolites in the Naked Mole-Rat (Heterocephalus glaber) [PDF]
Animals, 2023 The naked mole-rat (Heterocephalus glaber) occurs in colonies with a distinct dominance hierarchy, including one dominant, breeding female (the queen), 1–3 breeding males, and non-reproductive subordinates of both sexes that are reproductively suppressed
Tshepiso Lesedi Majelantle +5 more
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Naked mole-rat macrophage polarization
Медицинская иммунологияThe naked mole-rat (NMR) is a unique long-lived rodent with low cancer incidence. Understanding the molecular mechanisms that NMR evolved to control aging and tumorigenesis is important for biomedicine.
E. A. Gorshkova +4 more
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Naked mole-rat and Damaraland mole-rat exhibit lower respiration in mitochondria, cellular and organismal levels. [PDF]
Biochim Biophys Acta Bioenerg, 2022 AbstractNaked mole-rats (NMR) and Damaraland mole-rats (DMR) are the only two eusocial mammals known. Both species exhibit extraordinary longevity for their body size, high tolerance to hypoxia and oxidative stress and high reproductive output; these collectively defy the concept that all life-history traits should be negatively correlated.
Yap KN +7 more
europepmc +4 more sources